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Relative and Absolute Configuration of Allohedycaryol. Enantiospecific Total Synthesis of Its Enantiomer.

The Journal of organic chemistry

Zhabinskii VN, Minnaard AJ, Wijnberg JB, de Groot A.
PMID: 11667277
J Org Chem. 1996 Jun 14;61(12):4022-4027. doi: 10.1021/jo9602534.

The enantiomer of (+)-allohedycaryol, a germacrane alcohol isolated from giant fennel (Ferula communis L.), has been synthesized, thereby elucidating the relative and absolute stereochemistry of the natural product. The synthesis of (-)-allohedycaryol started from (+)-alpha-cyperone (5) which was available...

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