Dose-response : a publication of International Hormesis Society

Fatima I, Kanwal S, Mahmood T.
PMID: 30670935
Dose Response. 2019 Jan 08;17(1):1559325818813227. doi: 10.1177/1559325818813227. eCollection 2019.

The role of viral infection in developing cancer was determined in the start of 20th century. Until now, 8 different virus-associated cancers have been discovered and most of them progressed in immunosuppressed individuals. The aim of the present study...

Beilstein journal of organic chemistry

Knobloch T, Dräger G, Collisi W, Sasse F, Kirschning A.
PMID: 23015834
Beilstein J Org Chem. 2012;8:861-9. doi: 10.3762/bjoc.8.96. Epub 2012 Jun 11.

We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of...

Beilstein journal of organic chemistry

Harmrolfs K, Mancuso L, Drung B, Sasse F, Kirschning A.
PMID: 24605171
Beilstein J Org Chem. 2014 Mar 03;10:535-43. doi: 10.3762/bjoc.10.49. eCollection 2014.

The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a thiol linker by Huisgen-type cycloaddition which can principally be utilized to create tumor...