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Showing 1 to 12 of 1066 entries
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The plausibility design, quasi-experiments and real world research: a case study of artemisinin-based combination therapy in Tanzania

quasi-experiments

[No authors listed]
GSID: vR-vIIinkKQJ
SP Kachur, PW Geissler… - Evidence, Ethos and …, 2010 - Berghan London

No abstract available.

Severe idiosyncratic drug reactions with epidermal necrolysis: A 5-year study.

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India

Fadeyibi IO, Ademiluyi SA, Ajose FO, Jewo PI, Akinola OI.
PMID: 22279281
Indian J Plast Surg. 2011 Sep;44(3):467-73. doi: 10.4103/0970-0358.90824.

INTRODUCTION: Idiosyncratic drug reactions (IDRs) are unexpected responses to a drug. The spectrums of severe cutaneous reactions include Stevens-Johnson Syndrome (SJS), SJS/Lyell Syndrome and Toxic Epidermal Necrolysis (TEN). The conditions are associated with high mortality. This study was designed...

Water-soluble artemisinin derivatives as promising therapeutic immunosuppressants of autoimmune diseases.

Cellular & molecular immunology

Li H, Zuo J, Tang W.
PMID: 28890548
Cell Mol Immunol. 2017 Sep 11; doi: 10.1038/cmi.2017.87. Epub 2017 Sep 11.

No abstract available.

The threat of antimalarial drug resistance.

Tropical diseases, travel medicine and vaccines

Hanboonkunupakarn B, White NJ.
PMID: 28883954
Trop Dis Travel Med Vaccines. 2016 Jul 07;2:10. doi: 10.1186/s40794-016-0027-8. eCollection 2016.

The battle between man and malaria has continued for thousands of years. Antimalarial drugs are essential weapons to fight the disease, but their efficacy is threatened by drug resistance which continues to emerge creating a major obstacle to malaria...

Early treatment failure in concurrent dengue and mixed malaria species infection with suspected resistance to artemisinin combination therapy from a tertiary care center in Delhi: a case report.

International medical case reports journal

Saksena R, Matlani M, Singh V, Kumar A, Anveshi A, Kumar D, Gaind R.
PMID: 28860870
Int Med Case Rep J. 2017 Aug 16;10:289-294. doi: 10.2147/IMCRJ.S139729. eCollection 2017.

BACKGROUND: Concurrent dengue and mixed malaria infections in a single patient present with overlapping clinical manifestations which pose a diagnostic challenge and management dilemma in areas of common endemicities.METHODS: We report a case of a young male who tested...

Stable Production of the Antimalarial Drug Artemisinin in the Moss .

Frontiers in bioengineering and biotechnology

Khairul Ikram NKB, Beyraghdar Kashkooli A, Peramuna AV, van der Krol AR, Bouwmeester H, Simonsen HT.
PMID: 28861412
Front Bioeng Biotechnol. 2017 Aug 15;5:47. doi: 10.3389/fbioe.2017.00047. eCollection 2017.

Malaria is a real and constant danger to nearly half of the world's population of 7.4 billion people. In 2015, 212 million cases were reported along with 429,000 estimated deaths. The World Health Organization recommends artemisinin-based combinatorial therapies, and...

Proteomic analysis of the medicinal plant Artemisia annua: Data from leaf and trichome extracts.

Data in brief

Bryant L, Patole C, Cramer R.
PMID: 26977431
Data Brief. 2016 Feb 23;7:325-31. doi: 10.1016/j.dib.2016.02.038. eCollection 2016 Jun.

This article contains raw and processed data related to research published by Bryant et al.[1]. Data was obtained by MS-based proteomics, analysing trichome-enriched, trichome-depleted and whole leaf samples taken from the medicinal plant Artemisia annua and searching the acquired...

A Drug Combination Screen Identifies Drugs Active against Amoxicillin-Induced Round Bodies of In Vitro Borrelia burgdorferi Persisters from an FDA Drug Library.

Frontiers in microbiology

Feng J, Shi W, Zhang S, Sullivan D, Auwaerter PG, Zhang Y.
PMID: 27242757
Front Microbiol. 2016 May 23;7:743. doi: 10.3389/fmicb.2016.00743. eCollection 2016.

Although currently recommended antibiotics for Lyme disease such as doxycycline or amoxicillin cure the majority of the patients, about 10-20% of patients treated for Lyme disease may experience lingering symptoms including fatigue, pain, or joint and muscle aches. Under...

Treatment-seeking Paths in the Management of Severe Malaria in Children under 15 Years of Age Treated in Reference Hospitals of Kinshasa, Democratic Republic of Congo.

Tropical medicine and health

Ilunga-Ilunga F, Levêque A, Ngongo LO, Laokri S, Dramaix M.
PMID: 25729313
Trop Med Health. 2015 Mar;43(1):11-9. doi: 10.2149/tmh.2014-19. Epub 2014 Oct 16.

BACKGROUND: In the Democratic Republic of Congo (DRC), few studies have focused on treatment-seeking paths selected by caretakers for the management of severe childhood malaria in an urban environment. The present study aims at describing the treatment-seeking paths according...

Dihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy.

Oncology letters

Zhang ZS, Wang J, Shen YB, Guo CC, Sai KE, Chen FR, Mei X, Han FU, Chen ZP.
PMID: 26171034
Oncol Lett. 2015 Jul;10(1):379-383. doi: 10.3892/ol.2015.3183. Epub 2015 May 06.

Artemisinin, a powerful antimalarial medicine, is extracted from the Chinese herb,

The availability of six tracer medicines in private medicine outlets in Uganda.

Journal of pharmaceutical policy and practice

Birabwa C, Murison J, Evans V, Obua C, Agaba A, Waako P, Pollock A.
PMID: 25667747
J Pharm Policy Pract. 2014 Dec 08;7(1):18. doi: 10.1186/s40545-014-0018-y. eCollection 2014.

OBJECTIVES: Many low income countries struggle to provide safe and effective medicines due to poor public health care infrastructure, budgetary constraints, and lack of human resource capacity. Private sector pharmacies and drug shops are used by a majority of...

Two distinct and competitive pathways confer the cellcidal actions of artemisinins.

Microbial cell (Graz, Austria)

Sun C, Li J, Cao Y, Long G, Zhou B.
PMID: 28357259
Microb Cell. 2015 Jan 02;2(1):14-25. doi: 10.15698/mic2015.01.181.

The biological actions of artemisinin (ART), an antimalarial drug derived from

Showing 1 to 12 of 1066 entries