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The endopeptidase inhibitor, candoxatril, and its therapeutic potential in the treatment of chronic cardiac failure in man.

Expert opinion on investigational drugs

McDowell G, Nicholls DP.
PMID: 15992061
Expert Opin Investig Drugs. 1999 Jan;8(1):79-84. doi: 10.1517/13543784.8.1.79.

Candoxatril (UK-79300) is the orally-active prodrug of candoxatrilat (UK-73967), the active enantiomer of (+/-)candoxatrilat (UK-69578), a potent neutral endopeptidase (NEP) inhibitor. This article describes the rationale behind the use of such a drug in the treatment of chronic heart...

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