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Showing 1 to 12 of 22 entries
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Evaluation of the in vitro Activity of Two Fourth-Generation Cephalosporins Against Bacterial Samples Isolated From Patients in Several Brazilian Hospitals.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Cereda RF, Sader HS, Barth AL, Segura A, Kage R, Novakonski A, Pignatari AC.
PMID: 11084667
Braz J Infect Dis. 1999 Oct;3(5):189-196.

Cefpirome and cefepime are two fourth-generation cephalosporins recently introduced in Brazil. They have a very similar range of in vitro antimicrobial activity, but some differences have been noticed. The goal of this study was to compare the in vitro...

Influence of experimentally induced fever on the disposition of cefpirome in buffalo calves.

Environmental toxicology and pharmacology

Rajput N, Dumka VK, Sandhu HS.
PMID: 21791379
Environ Toxicol Pharmacol. 2008 Nov;26(3):305-8. doi: 10.1016/j.etap.2008.06.003. Epub 2008 Jun 27.

The influence of Escherichia coli endotoxin-induced fever on the disposition of cefpirome was investigated in five male buffalo calves following a single intravenous dose of 10mgkg(-1). Blood samples were collected from 1min to 24h of drug administration. The drug...

Evaluation of the Cephalosporins, Cefepime, Cefpirome and Ceftazidime, against Clinical Isolates of Imipenem-Resistant Pseudomonas aeruginosa.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Sader HS, Cerbara EF, Luz D, Hashimoto A.
PMID: 11084674
Braz J Infect Dis. 1999 Dec;3(6):231-237.

The level of resistance to imipenem in our institution has increased significantly in recent years, particularly in isolates of Pseudomonas aeruginosa. At present, 30% to 40% of P. aeruginosa isolated in clinical samples are imipenem resistant. The objective of...

Bactericidal activity of three beta-lactams alone or in combination with a beta-lactamase inhibitor and two aminoglycosides against Klebsiella pneumoniae harboring extended-spectrum beta-lactamases.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Roussel-Delvallez M, Wallet F, Dao A, Marti V, Sirot D, Beaucaire G, Courcol R.
PMID: 11864245
Clin Microbiol Infect. 1998;4(10):570-576. doi: 10.1111/j.1469-0691.1998.tb00039.x.

OBJECTIVE: To study the bactericidal activity of beta-lactam antibiotics (imipenem, cefepime, cefpirome) alone or in combination with a beta-lactamase inhibitor (sulbactam) in the presence or absence of aminoglycoside (amikacin or isepamicin) against Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases (ESBLs)....

Roles of MexXY- and MexAB-multidrug efflux pumps in intrinsic multidrug resistance of Pseudomonas aeruginosa PAO1.

The Journal of general and applied microbiology

Morita Y, Kimura N, Mima T, Mizushima T, Tsuchiya T.
PMID: 12483565
J Gen Appl Microbiol. 2001 Feb;47(1):27-32. doi: 10.2323/jgam.47.27.

To envisage the roles of MexXY- and MexAB-multidrug efflux pumps in the intrinsic multidrug resistance of wild-type strain Pseudomonas aeruginosa PAO1, we constructed mutants lacking either individual or both efflux pumps. A mutant lacking MexXY showed increased susceptibility to...

Clinical evaluation of monotherapy with cefpirome for infections complicating hematological disorders.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Yano K, Nakano Y.
PMID: 29681352
J Infect Chemother. 1996;2(2):75-78. doi: 10.1007/BF02350844. Epub 2014 Apr 05.

The clinical effects of cefpirome (CPR) monotherapy were evaluated in 38 infected patients with hematological diseases. The underlying diseases of the patients were chiefly acute leukemia, myelodysplastic syndrome, malignant lymphoma, and aplastic anemia, and 18 patients were clinically neutropenic...

Antibiotic Prophylaxis Using Cefpirome Sulfate in Gynecologic Surgery and Elimination Rate of Enterococcus faecalis from the Vagina.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Kubota T, Utsuono S.
PMID: 29681364
J Infect Chemother. 1996;1(3):197-200. doi: 10.1007/BF02350649. Epub 2014 Apr 05.

Seventy-five patients undergoing total abdominal hysterectomy were given 1g of cefpirome sulfate (CPR) intravenously twice daily from immediately after surgery through the second postoperative day (CPR group). The results were compared with data from our previous study (1984-1985) in...

In vitro activity of cefpirome: a new fourth generation cephalosporin.

Indian journal of medical microbiology

Chaudhury A.
PMID: 17642976
Indian J Med Microbiol. 2003 Jan-Mar;21(1):52-5.

This study was carried out to find the efficacy of Cefpirome in an Indian setting in a tertiary care referral hospital. A total of 516 bacterial isolates from various clinical specimens were tested against cefpirome (Cpo) and compared against...

Cefpirome---vancomycin combination in methicillin-resistant Staphylococcus aureus infection.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Raymond J, Bergeret M, Sauve-Martin H, Iniguez JL, Gendrel D.
PMID: 11864286
Clin Microbiol Infect. 1998 Feb;4(12):733-734. doi: 10.1111/j.1469-0691.1998.tb00663.x.

No abstract available.

Effects of a new cephalosporin, cefpirome (HR 810), on ATPase activities of rabbit renal proximal tubule suspensions: Comparison with cephaloridine and cefotaxime.

Toxicology in vitro : an international journal published in association with BIBRA

Olivier MF, Martin C, Dutertre-Catella H, Thevenin M, Warnet JM, Vannier B, Claude JR, Podevin RA.
PMID: 20732109
Toxicol In Vitro. 1992 Mar;6(2):175-6. doi: 10.1016/0887-2333(92)90012-g.

The effect of cefpirome (HR 810), a new cephalosporin, on ATPase activities of rabbit renal proximal tubules has been measured and compared with that of cephaloridine and cefotaxime. Only cephaloridine, the nephrotoxicity of which is well established in the...

Molecular Features of Non-Selective Small Molecule Antagonists of the Bradykinin Receptors.

Pharmaceuticals (Basel, Switzerland)

Rasaeifar B, Gomez-Gutierrez P, Perez JJ.
PMID: 32967280
Pharmaceuticals (Basel). 2020 Sep 21;13(9). doi: 10.3390/ph13090259.

Angiotensin converting enzyme 2 (ACE2) downregulation is a key negative factor for the severity of lung edema and acute lung failure observed in patients infected with SARS-CoV-2. ACE2 downregulation affects the levels of diverse peptide mediators of the renin-agiotensin-aldestosterone...

The Comparative In Vitro Activity of FK-037 (Cefoselis), a New Broad-Spectrum Cephalosporin.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

King A, Bethune L, Phillips I.
PMID: 11866715
Clin Microbiol Infect. 1995 Sep;1(1):13-17. doi: 10.1111/j.1469-0691.1995.tb00018.x.

FK-037, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. The activity of FK---037 was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Methicillin-resistant staphylococci were...

Showing 1 to 12 of 22 entries