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Showing 1 to 12 of 31 entries
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Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Naeshiro N, Aikata H, Hyogo H, Kan H, Fujino H, Kobayashi T, Fukuhara T, Honda Y, Nakahara T, Ohno A, Miyaki D, Murakami E, Kawaoka T, Tsuge M, Hiraga N, Hiramatsu A, Imamura M, Kawakami Y, Ochi H, Chayama K.
PMID: 25088236
Hepatol Res. 2015 Jun;45(6):656-62. doi: 10.1111/hepr.12400. Epub 2014 Sep 02.

AIM: To assess the efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis.METHODS: A consecutive 26 cirrhotic patients with PVT were enrolled in this retrospective cohort...

Heparin-induced thrombocytopenia in the pediatric population: a review of current literature.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Vakil NH, Kanaan AO, Donovan JL.
PMID: 23118656
J Pediatr Pharmacol Ther. 2012 Jan;17(1):12-30. doi: 10.5863/1551-6776-17.1.12.

Heparin-induced thrombocytopenia is a rare and serious reaction to unfractionated heparin and low-molecular-weight heparins in children. Quick recognition, discontinuation of heparin, and subsequent treatment with an alternative anticoagulant are essential steps to prevent serious complications such as thrombus and...

The effect of unfractionated heparin, enoxaparin, and danaparoid on lupus anticoagulant testing: Can activated carbon eliminate false-positive results?.

Research and practice in thrombosis and haemostasis

De Kesel PMM, Devreese KMJ.
PMID: 31989098
Res Pract Thromb Haemost. 2019 Dec 10;4(1):161-168. doi: 10.1002/rth2.12264. eCollection 2020 Jan.

BACKGROUND: Heparins and heparinoids interfere with functional clotting assays used for lupus anticoagulant (LAC) detection. However, current guidelines for LAC testing do not provide clear guidance on this matter.OBJECTIVES: We aimed to assess to effect of unfractionated heparin (UFH),...

Primary breast angiosarcoma with disseminated intravascular coagulation is successfully treated with self-subcutaneous unfractionated heparin calcium injection: A case report.

Molecular and clinical oncology

Yagi T, Nakamura H, Wakamatsu T, Imura Y, Tamiya H, Sabe H, Yamashita K, Watanabe M, Takenaka S.
PMID: 33815793
Mol Clin Oncol. 2021 May;14(5):104. doi: 10.3892/mco.2021.2266. Epub 2021 Mar 17.

Angiosarcoma is a rare sarcoma with a poor prognosis and is prone to disseminated intravascular coagulation (DIC), where DIC often interferes with chemotherapy. Primary angiosarcoma of the breast (PASB) is a type of angiosarcoma that is located in mammary...

Successful Use of Alternative Anticoagulants in the Management of Heparin-induced Thrombocytopenia with Thrombotic Complications: Report of 5 cases and review of literature.

Sultan Qaboos University medical journal

Alkindi S, Smith OP, Enright H.
PMID: 22087382
Sultan Qaboos Univ Med J. 2011 Aug;11(3):391-8. Epub 2011 Aug 15.

Heparin is one of the most frequently used anticoagulants. It is easy to use, but can be associated with life-threatening side effects. One of these is heparin-induced thrombocytopenia syndrome (HITS), which develops in about 3-5% of patients exposed to...

Adenovirus-Vectored COVID-19 Vaccine-Induced Immune Thrombosis of Carotid Artery: A Case Report.

Neurology

Walter U, Fuchs M, Grossmann A, Walter M, Thiele T, Storch A, Wittstock M.
PMID: 34312301
Neurology. 2021 Jul 26; doi: 10.1212/WNL.0000000000012576. Epub 2021 Jul 26.

OBJECTIVE: Venous thromboses and thrombocytopenia after vaccination with the adenovirus-vectored COVID-19 vaccine ChAdOx1 nCov-19 (AstraZeneca) have been linked to serum antibodies against platelet factor 4 (PF4)-polyanion complexes. We here report vaccine-induced isolated carotid arterial thrombosis.METHODS: Imaging and laboratory findings,...

Aortocoronary Vein Bypass in a Patient with Type II Heparin-Associated Thrombopenia: A Case Report.

The International journal of angiology : official publication of the International College of Angiology, Inc

Christiansen S, Geiger A, Splittgerber FH, Reidemeister JC.
PMID: 9585467
Int J Angiol. 1998 May;7(3):268-70. doi: 10.1007/BF01617410.

Two types of heparin-associated thrombopenia (HAT) can be distinguished. Patients with type II HAT (HAT II) present a particularly difficult management problem when they require full anticoagulation. There is no consensus about the proper anticoagulation management for patients with...

Heparin-induced Thrombocytopenia.

Current treatment options in cardiovascular medicine

Gerhard-Herman M.
PMID: 11341867
Curr Treat Options Cardiovasc Med. 2001 Jun;3(3):215-224. doi: 10.1007/s11936-001-0040-7.

Treatment with heparin is associated with two types of thrombocytopenia. The most worrisome of these is the immune-mediated heparin-induced thrombocytopenia (HIT type II). Suspicion of HIT type II mandates immediate cessation of heparin administration and consideration of an alternative...

Intravenous immunoglobulin therapy for aspirin-heparinoid-resistant antiphospholipid syndrome.

Reproductive medicine and biology

Shimada S, Yamada H, Atsumi T, Yamada T, Sakuragi N, Minakami H.
PMID: 29699347
Reprod Med Biol. 2010 Jun 15;9(4):217-221. doi: 10.1007/s12522-010-0056-3. eCollection 2010 Dec.

We encountered a woman who had a history of repeated fetal losses and positive tests for lupus anticoagulant, phosphatidylserine-dependent antiprothrombin (aPS/PT) IgG, IgM and kininogen-dependent antiphosphatidylethanolamine (aPE) IgG, IgM. Her previous pregnancy had ended in intrauterine fetal death at...

Heparin-induced thrombocytopenia: recommendations for optimal use of recombinant hirudin.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Lubenow N, Greinacher A.
PMID: 18034563
BioDrugs. 2000 Aug;14(2):109-25. doi: 10.2165/00063030-200014020-00005.

Recombinant hirudins have a definite role in the treatment of patients with heparin-induced thrombocytopenia (HIT). The most important adverse effects are haemorrhages and the induction of antihirudin antibodies. Major haemorrhages were not significantly increased in patients with HIT compared...

[Heparin-induced thrombocytopenia: Update].

La Revue de medecine interne

Camoin-Jau L, Mariotti A, Suchon P, Morange PE.
PMID: 34535328
Rev Med Interne. 2021 Sep 14; doi: 10.1016/j.revmed.2021.08.011. Epub 2021 Sep 14.

Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy. It is due to the synthesis of antibodies most often directed against platelet factor 4 (FP4) modified by heparin (H). HIT is manifested by a platelet count fall, associated...

Fatal vaccine-induced immune thrombotic thrombocytopenia (VITT) post Ad26.COV2.S: first documented case outside US.

Infection

Rodriguez EVC, Bouazza FZ, Dauby N, Mullier F, d'Otreppe S, Jissendi Tchofo P, Bartiaux M, Sirjacques C, Roman A, Hermans C, Cliquennois M.
PMID: 34626338
Infection. 2021 Oct 09; doi: 10.1007/s15010-021-01712-8. Epub 2021 Oct 09.

PURPOSE: We reported the first described post Ad26.COV2.S (Janssen, Johnson & Johnson) vaccine-induced immune thrombocytopenia (VITT) case outside US.  CASE DESCRIPTION: CA young woman without any medical history presented association of deep vein thrombosis and thrombocytopenia at day 10...

Showing 1 to 12 of 31 entries