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Showing 1 to 7 of 7 entries
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Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayés M, Rabasseda X, Prous JR.
PMID: 15148527
Methods Find Exp Clin Pharmacol. 2004 Apr;26(3):211-44.

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies Knowledge Area of Prous Science Integrity(R), the drug...

Correction to: SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin.

Apoptosis : an international journal on programmed cell death

Hu C, Tan H, Lin Q, Abudupataer M, Zhao Y, Li J, Gu J, Cheng D, Wang C, Zhu K, Lai H.
PMID: 31422488
Apoptosis. 2019 Oct;24(9):756-757. doi: 10.1007/s10495-019-01563-7.

The original version of this article unfortunately contains errors in Figure 4. An incorrect Figure 4D is published which is actually a repetition of Figure 2C (i.e., apoptosis rate in control vs. H2O2-treated group). The correct Figure 4D should...

Elucidating Duramycin's Bacterial Selectivity and Mode of Action on the Bacterial Cell Envelope.

Frontiers in microbiology

Hasim S, Allison DP, Mendez B, Farmer AT, Pelletier DA, Retterer ST, Campagna SR, Reynolds TB, Doktycz MJ.
PMID: 29491859
Front Microbiol. 2018 Feb 14;9:219. doi: 10.3389/fmicb.2018.00219. eCollection 2018.

The use of naturally occurring antimicrobial peptides provides a promising route to selectively target pathogenic agents and to shape microbiome structure. Lantibiotics, such as duramycin, are one class of bacterially produced peptidic natural products that can selectively inhibit the...

Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection.

Molecular therapy oncolytics

Zhang L, Suksanpaisan L, Jiang H, DeGrado TR, Russell SJ, Zhao M, Peng KW.
PMID: 31890867
Mol Ther Oncolytics. 2019 Oct 10;15:178-185. doi: 10.1016/j.omto.2019.10.002. eCollection 2019 Dec 20.

Noninvasive dual-imaging methods that provide an early readout on tumor permissiveness to virus infection and tumor cell death could be valuable in optimizing development of oncolytic virotherapies. Here, we have used the sodium iodide symporter (NIS) and

Constitutive oxidants from hepatocytes of male iPLA2β-null mice increases the externalization of phosphatidylethanolamine on plasma membrane.

Free radical research

Wong HY, Langlotz M, Gan-Schreier H, Xu W, Staffer S, Tuma-Kellner S, Liebisch G, Merle U, Chamulitrat W.
PMID: 34696671
Free Radic Res. 2021 Jun;55(6):625-633. doi: 10.1080/10715762.2021.1987426.

We have found that group VIA calcium-independent phospholipase A2 (iPLA2β) has specificity for hydrolysis of phosphatidylethanolamine (PE) in mouse livers. Phospholipids (PLs) are transported to plasma membrane and some PLs including PE are externalized to maintain membrane PL asymmetry....

A One-Step Staining Probe for Phosphatidylethanolamine.

Chembiochem : a European journal of chemical biology

Hou S, Johnson SE, Zhao M.
PMID: 26224023
Chembiochem. 2015 Sep 07;16(13):1955-1960. doi: 10.1002/cbic.201500127. Epub 2015 Jul 23.

Phosphatidylethanolamine (PE) is an abundant phospholipid in cellular membranes, but relatively little is known about the kinetics of PE in biological membrane systems. Characterizing PE on a cellular level has been challenging owing to a lack of proper molecular...

Bactericidal urea crown ethers target phosphatidylethanolamine membrane lipids.

Organic & biomolecular chemistry

Herschede SR, Gneid H, Dent T, Jaeger EB, Lawson LB, Busschaert N.
PMID: 33949594
Org Biomol Chem. 2021 May 05;19(17):3838-3843. doi: 10.1039/d1ob00263e.

An increasing number of people are infected with antibiotic-resistant bacteria each year, sometimes with fatal consequences. In this manuscript, we report a novel urea-functionalized crown ether that can bind to the bacterial lipid phosphatidylethanolamine (PE), facilitate PE flip-flop and...

Showing 1 to 7 of 7 entries