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Integrated optical biosensor for detection of multivalent proteins.

Optics letters

Kelly D, Grace KM, Song X, Swanson BI, Frayer D, Mendes SB, Peyghambarian N.
PMID: 18079915
Opt Lett. 1999 Dec 01;24(23):1723-5. doi: 10.1364/ol.24.001723.

We have developed a simple, highly sensitive and specific optical waveguide sensor for the detection of multivalent proteins. The optical biosensor is based on optically tagged glycolipid receptors embedded within a fluid phospholipid bilayer membrane formed upon the surface...

Sphingomyelinase-Mediated Multitimescale Clustering of Ganglioside GM1 in Heterogeneous Lipid Membranes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Lee HR, Choi SQ.
PMID: 34473415
Adv Sci (Weinh). 2021 Oct;8(20):e2101766. doi: 10.1002/advs.202101766. Epub 2021 Sep 02.

Several signaling processes in the plasma membrane are intensified by ceramides that are formed by sphingomyelinase-mediated hydrolysis of sphingomyelin. These ceramides trigger clustering of signaling-related biomolecules, but how they concentrate such biomolecules remains unclear. Here, the spatiotemporal localization of...

Showing 1 to 2 of 2 entries