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Showing 1 to 6 of 6 entries
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On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

O'Dwyer PJ, Box KJ, Imanidis G, Vertzoni M, Reppas C.
PMID: 34628003
Eur J Pharm Sci. 2021 Oct 07;168:106034. doi: 10.1016/j.ejps.2021.106034. Epub 2021 Oct 07.

A small-scale two-stage biphasic system, a small-scale two-stage dissolution-permeation system, the Erweka mini-paddle apparatus, and the BioGIT system were evaluated for their usefulness in assessing the intraluminal performance of two low solubility drugs in the fasted state, one with...

Stability of medicines after repackaging into multicompartment compliance aids: eight criteria for detection of visual alteration.

Drugs & therapy perspectives : for rational drug selection and use

Albert V, Lanz M, Imanidis G, Hersberger KE, Arnet I.
PMID: 28989276
Drugs Ther Perspect. 2017;33(10):487-496. doi: 10.1007/s40267-017-0431-9. Epub 2017 Jul 26.

INTRODUCTION: Multicompartment compliance aids (MCA) are widely used by patients. They support the management of medication and reduce unintentional nonadherence. MCA are filled with medicines unpacked from their original packaging. Swiss pharmacists currently provide MCA for 1-2 weeks, although...

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development.

Pharmaceutics

O'Dwyer PJ, Imanidis G, Box KJ, Reppas C.
PMID: 32188116
Pharmaceutics. 2020 Mar 16;12(3). doi: 10.3390/pharmaceutics12030272.

A small-scale biphasic dissolution setup and a small-scale dissolution-permeation (D-P) setup were evaluated for their usefulness in simulating the luminal precipitation of three lipophilic weak bases-dipyridamole, ketoconazole and itraconazole. The transition from the gastric to intestinal environment was incorporated...

On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

O'Dwyer PJ, Box KJ, Imanidis G, Vertzoni M, Reppas C.
PMID: 34628003
Eur J Pharm Sci. 2022 Jan 01;168:106034. doi: 10.1016/j.ejps.2021.106034. Epub 2021 Oct 07.

A small-scale two-stage biphasic system, a small-scale two-stage dissolution-permeation system, the Erweka mini-paddle apparatus, and the BioGIT system were evaluated for their usefulness in assessing the intraluminal performance of two low solubility drugs in the fasted state, one with...

On the usefulness of four in vitro methods in assessing the intraluminal performance of poorly soluble, ionisable compounds in the fasted state.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

O'Dwyer PJ, Box KJ, Imanidis G, Vertzoni M, Reppas C.
PMID: 34628003
Eur J Pharm Sci. 2022 Jan 01;168:106034. doi: 10.1016/j.ejps.2021.106034. Epub 2021 Oct 07.

A small-scale two-stage biphasic system, a small-scale two-stage dissolution-permeation system, the Erweka mini-paddle apparatus, and the BioGIT system were evaluated for their usefulness in assessing the intraluminal performance of two low solubility drugs in the fasted state, one with...

Repartition of oil miscible and water soluble UV filters in an applied sunscreen film determined by confocal Raman microspectroscopy.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

Sohn M, Buehler T, Imanidis G.
PMID: 27256969
Photochem Photobiol Sci. 2016 Jul 06;15(7):861-71. doi: 10.1039/c6pp00024j.

Photoprotection provided by topical sunscreens is expressed by the sun protection factor (SPF) which depends primarily on the UV filters contained in the product and the applied sunscreen amount. Recently, the vehicle was shown to significantly impact film thickness...

Showing 1 to 6 of 6 entries