Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 11 of 11 entries
Sorted by: Best Match Show Resources per page
α-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic α-CH.

Organic letters

Thatikonda T, Deepake SK, Das U.
PMID: 30939020
Org Lett. 2019 Apr 19;21(8):2532-2535. doi: 10.1021/acs.orglett.9b00224. Epub 2019 Apr 02.

A method for the direct oxidation of various N-aryl tetrahydroisoquinolines and isoindolines to the corresponding lactams using α-angelica lactone as a catalyst was developed. The utility of the method was further demonstrated by synthesis of indoprofen and indobufen.

Cite
Thatikonda T, Deepake SK, Das U. α-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic α-CH. Org Lett. 2019;21(8):2532-2535doi: 10.1021/acs.orglett.9b00224.
Thatikonda, T., Deepake, S. K., & Das, U. (2019). α-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic α-CH. Organic letters, 21(8), 2532-2535. https://doi.org/10.1021/acs.orglett.9b00224
Thatikonda, Thanusha, et al. "α-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic α-CH." Organic letters vol. 21,8 (2019): 2532-2535. doi: https://doi.org/10.1021/acs.orglett.9b00224
Thatikonda T, Deepake SK, Das U. α-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic α-CH. Org Lett. 2019 Apr 19;21(8):2532-2535. doi: 10.1021/acs.orglett.9b00224. Epub 2019 Apr 02. PMID: 30939020.
Copy Download .nbib Format: NLM
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y.
PMID: 33512659
J Neuroimmune Pharmacol. 2021 Jan 29; doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29.

Increasing studies showed that several anti-platelet drugs turned out to be a promising strategy for inflammatory response. In this study, we investigated the protective efficiency of pretreatment of indobufen or aspirin combined with clopidogrel or ticagrelor (IACT) on cerebral...

Cite
Li F, Xu D, Hou K, et al. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021;doi: 10.1007/s11481-020-09978-9.
Li, F., Xu, D., Hou, K., Gou, X., Lv, N., Fang, W., & Li, Y. (2021). Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, . https://doi.org/10.1007/s11481-020-09978-9
Li, Fengyang, et al. "Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology vol. (2021). doi: https://doi.org/10.1007/s11481-020-09978-9
Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021 Jan 29; doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29. PMID: 33512659.
Copy Download .nbib Format: NLM
[Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors].

Giornale italiano di cardiologia (2006)

Bianco M, Biolè C, Spirito A, Destefanis P, Luciano A, Montagna L, Cerrato E.
PMID: 34985465
G Ital Cardiol (Rome). 2022 Jan;23(1):75-79. doi: 10.1714/3715.37065.

Aspirin hypersensitivity is a neglected issue, especially in the setting of ST-elevation myocardial infarction (STEMI). Nevertheless, in such context a prompt platelet inhibition remains crucial. We report the case of a patient presenting with STEMI, aspirin hypersensitivity and emesis...

Cite
Bianco M, Biolè C, Spirito A, et al. Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. G Ital Cardiol (Rome). 2022;23(1):75-79doi: 10.1714/3715.37065.
Bianco, M., Biolè, C., Spirito, A., Destefanis, P., Luciano, A., Montagna, L., & Cerrato, E. (2022). Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. Giornale italiano di cardiologia (2006), 23(1), 75-79. https://doi.org/10.1714/3715.37065
Bianco, Matteo, et al. "Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12." [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. Giornale italiano di cardiologia (2006) vol. 23,1 (2022): 75-79. doi: https://doi.org/10.1714/3715.37065
Bianco M, Biolè C, Spirito A, Destefanis P, Luciano A, Montagna L, Cerrato E. Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. G Ital Cardiol (Rome). 2022 Jan;23(1):75-79. doi: 10.1714/3715.37065. Italian. PMID: 34985465.
Copy Download .nbib Format: NLM
Prediction of the human .

Translational and clinical pharmacology

Noh YH, Han S, Choe S, Jung JA, Jung JA, Hwang AK, Lim HS.
PMID: 32055570
Transl Clin Pharmacol. 2018 Dec;26(4):160-165. doi: 10.12793/tcp.2018.26.4.160. Epub 2018 Dec 19.

Indobufen (Ibustrin®), a reversible inhibitor of platelet aggregation, exists in two enantiomeric forms in 1:1 ratio. Here, we characterized the anti-platelet effect of S- and R-indobufen using response surface modeling using NONMEM® and predicted the therapeutic doses exerting the...

Cite
Noh YH, Han S, Choe S, et al. Prediction of the human . Transl Clin Pharmacol. 2018;26(4):160-165doi: 10.12793/tcp.2018.26.4.160.
Noh, Y. H., Han, S., Choe, S., Jung, J. A., Jung, J. A., Hwang, A. K., & Lim, H. S. (2018). Prediction of the human . Translational and clinical pharmacology, 26(4), 160-165. https://doi.org/10.12793/tcp.2018.26.4.160
Noh, Yook-Hwan, et al. "Prediction of the human ." Translational and clinical pharmacology vol. 26,4 (2018): 160-165. doi: https://doi.org/10.12793/tcp.2018.26.4.160
Noh YH, Han S, Choe S, Jung JA, Jung JA, Hwang AK, Lim HS. Prediction of the human . Transl Clin Pharmacol. 2018 Dec;26(4):160-165. doi: 10.12793/tcp.2018.26.4.160. Epub 2018 Dec 19. PMID: 32055570; PMCID: PMC6989252.
Copy Download .nbib Format: NLM
Copper-promoted direct amidation of isoindolinone scaffolds by sodium persulfate.

Organic & biomolecular chemistry

Lai H, Xu J, Lin J, Zha D.
PMID: 34308463
Org Biomol Chem. 2021 Sep 15;19(35):7621-7626. doi: 10.1039/d1ob01054a.

Isoindolinones are ubiquitous structural motifs in natural products and pharmaceuticals. Establishing an efficient method for structural modification of isoindolinones could significantly facilitate new drug development. Herein, we describe copper-promoted direct amidation of isoindolinone scaffolds mediated by sodium persulfate. The...

Cite
Lai H, Xu J, Lin J, et al. Copper-promoted direct amidation of isoindolinone scaffolds by sodium persulfate. Org Biomol Chem. 2021;19(35):7621-7626doi: 10.1039/d1ob01054a.
Lai, H., Xu, J., Lin, J., & Zha, D. (2021). Copper-promoted direct amidation of isoindolinone scaffolds by sodium persulfate. Organic & biomolecular chemistry, 19(35), 7621-7626. https://doi.org/10.1039/d1ob01054a
Lai, Huifang, et al. "Copper-promoted direct amidation of isoindolinone scaffolds by sodium persulfate." Organic & biomolecular chemistry vol. 19,35 (2021): 7621-7626. doi: https://doi.org/10.1039/d1ob01054a
Lai H, Xu J, Lin J, Zha D. Copper-promoted direct amidation of isoindolinone scaffolds by sodium persulfate. Org Biomol Chem. 2021 Sep 15;19(35):7621-7626. doi: 10.1039/d1ob01054a. PMID: 34308463.
Copy Download .nbib Format: NLM
[Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors].

Giornale italiano di cardiologia (2006)

Bianco M, Biolè C, Spirito A, Destefanis P, Luciano A, Montagna L, Cerrato E.
PMID: 34985465
G Ital Cardiol (Rome). 2022 Jan;23(1):75-79. doi: 10.1714/3715.37065.

Aspirin hypersensitivity is a neglected issue, especially in the setting of ST-elevation myocardial infarction (STEMI). Nevertheless, in such context a prompt platelet inhibition remains crucial. We report the case of a patient presenting with STEMI, aspirin hypersensitivity and emesis...

Cite
Bianco M, Biolè C, Spirito A, et al. Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. G Ital Cardiol (Rome). 2022;23(1):75-79doi: 10.1714/3715.37065.
Bianco, M., Biolè, C., Spirito, A., Destefanis, P., Luciano, A., Montagna, L., & Cerrato, E. (2022). Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. Giornale italiano di cardiologia (2006), 23(1), 75-79. https://doi.org/10.1714/3715.37065
Bianco, Matteo, et al. "Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12." [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. Giornale italiano di cardiologia (2006) vol. 23,1 (2022): 75-79. doi: https://doi.org/10.1714/3715.37065
Bianco M, Biolè C, Spirito A, Destefanis P, Luciano A, Montagna L, Cerrato E. Gestione dell’infarto miocardico con sopraslivellamento del tratto ST in un paziente con ipersensibilità all’aspirina senza l’uso di inibitori orali del recettore P2Y12. [Management of ST-elevation myocardial infarction in a patient with aspirin hypersensitivity without oral P2Y12 inhibitors]. G Ital Cardiol (Rome). 2022 Jan;23(1):75-79. doi: 10.1714/3715.37065. Italian. PMID: 34985465.
Copy Download .nbib Format: NLM
Stroke and atrial fibrillation: risks, prevention and therapy in the elderly.

Archives of gerontology and geriatrics

Raffaeli S, Paciaroni E.
PMID: 15374252
Arch Gerontol Geriatr. 1995 Jan-Feb;20(1):23-8. doi: 10.1016/0167-4943(94)00601-3.

Atrial fibrillation (AF) represents a high risk of systemic embolism, particularly of stroke (S). This is true not only when AF is associated with an organic cardiopathy, but also in the so-called nonvalvular AF (NVAF). Not all cases of...

Cite
Raffaeli S, Paciaroni E. Stroke and atrial fibrillation: risks, prevention and therapy in the elderly. Arch Gerontol Geriatr. 1995;20(1):23-8doi: 10.1016/0167-4943(94)00601-3.
Raffaeli, S., & Paciaroni, E. (1995). Stroke and atrial fibrillation: risks, prevention and therapy in the elderly. Archives of gerontology and geriatrics, 20(1), 23-8. https://doi.org/10.1016/0167-4943(94)00601-3
Raffaeli, S, and Paciaroni, E. "Stroke and atrial fibrillation: risks, prevention and therapy in the elderly." Archives of gerontology and geriatrics vol. 20,1 (1995): 23-8. doi: https://doi.org/10.1016/0167-4943(94)00601-3
Raffaeli S, Paciaroni E. Stroke and atrial fibrillation: risks, prevention and therapy in the elderly. Arch Gerontol Geriatr. 1995 Jan-Feb;20(1):23-8. doi: 10.1016/0167-4943(94)00601-3. PMID: 15374252.
Copy Download .nbib Format: NLM
Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis.

European journal of clinical pharmacology

Yang M, Ye Z, Mei L, Ullah I, Tan C, Wang G, Gu Q, Lu Y, Abdus S, Shi L, Gong X, Bai J, Eikelboom JW, Li C.
PMID: 34331551
Eur J Clin Pharmacol. 2021 Dec;77(12):1815-1823. doi: 10.1007/s00228-021-03177-y. Epub 2021 Jul 31.

PURPOSE: This study aimed to investigate the pharmacodynamic effects of indobufen and low-dose aspirin in patients with coronary atherosclerosis.METHODS: In the first phase, 218 patients with coronary atherosclerosis were randomly assigned to receive aspirin 100 mg once daily (standard...

Cite
Yang M, Ye Z, Mei L, et al. Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis. Eur J Clin Pharmacol. 2021;77(12):1815-1823doi: 10.1007/s00228-021-03177-y.
Yang, M., Ye, Z., Mei, L., Ullah, I., Tan, C., Wang, G., Gu, Q., Lu, Y., Abdus, S., Shi, L., Gong, X., Bai, J., Eikelboom, J. W., & Li, C. (2021). Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis. European journal of clinical pharmacology, 77(12), 1815-1823. https://doi.org/10.1007/s00228-021-03177-y
Yang, Mingwen, et al. "Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis." European journal of clinical pharmacology vol. 77,12 (2021): 1815-1823. doi: https://doi.org/10.1007/s00228-021-03177-y
Yang M, Ye Z, Mei L, Ullah I, Tan C, Wang G, Gu Q, Lu Y, Abdus S, Shi L, Gong X, Bai J, Eikelboom JW, Li C. Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis. Eur J Clin Pharmacol. 2021 Dec;77(12):1815-1823. doi: 10.1007/s00228-021-03177-y. Epub 2021 Jul 31. PMID: 34331551.
Copy Download .nbib Format: NLM
Platelet activation by cells isolated from human tumor tissues: effect of cyclooxygenase blockade.

Platelets

Pacchiarini L, Zucchella M, Tacconi F, Dionigi P, Brocchieri A, Scafa F, Grignani G.
PMID: 21043843
Platelets. 1993;4(4):207-11. doi: 10.3109/09537109309013219.

We have studied in a homologous system the effect on different platelet functions of cells isolated from 26 human tumor tissues (11 breast carcinomas, 11 colon carcinomas, 2 pancreatic carcinomas, 1 gastric carcinoma and 1 esophageal carcinoma). Tumor cells...

Cite
Pacchiarini L, Zucchella M, Tacconi F, et al. Platelet activation by cells isolated from human tumor tissues: effect of cyclooxygenase blockade. Platelets. 1993;4(4):207-11doi: 10.3109/09537109309013219.
Pacchiarini, L., Zucchella, M., Tacconi, F., Dionigi, P., Brocchieri, A., Scafa, F., & Grignani, G. (1993). Platelet activation by cells isolated from human tumor tissues: effect of cyclooxygenase blockade. Platelets, 4(4), 207-11. https://doi.org/10.3109/09537109309013219
Pacchiarini, L, et al. "Platelet activation by cells isolated from human tumor tissues: effect of cyclooxygenase blockade." Platelets vol. 4,4 (1993): 207-11. doi: https://doi.org/10.3109/09537109309013219
Pacchiarini L, Zucchella M, Tacconi F, Dionigi P, Brocchieri A, Scafa F, Grignani G. Platelet activation by cells isolated from human tumor tissues: effect of cyclooxygenase blockade. Platelets. 1993;4(4):207-11. doi: 10.3109/09537109309013219. PMID: 21043843.
Copy Download .nbib Format: NLM
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y.
PMID: 33512659
J Neuroimmune Pharmacol. 2021 Dec;16(4):835-853. doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29.

Increasing studies showed that several anti-platelet drugs turned out to be a promising strategy for inflammatory response. In this study, we investigated the protective efficiency of pretreatment of indobufen or aspirin combined with clopidogrel or ticagrelor (IACT) on cerebral...

Cite
Li F, Xu D, Hou K, et al. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021;16(4):835-853doi: 10.1007/s11481-020-09978-9.
Li, F., Xu, D., Hou, K., Gou, X., Lv, N., Fang, W., & Li, Y. (2021). Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 16(4), 835-853. https://doi.org/10.1007/s11481-020-09978-9
Li, Fengyang, et al. "Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology vol. 16,4 (2021): 835-853. doi: https://doi.org/10.1007/s11481-020-09978-9
Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021 Dec;16(4):835-853. doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29. PMID: 33512659.
Copy Download .nbib Format: NLM
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y.
PMID: 33512659
J Neuroimmune Pharmacol. 2021 Dec;16(4):835-853. doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29.

Increasing studies showed that several anti-platelet drugs turned out to be a promising strategy for inflammatory response. In this study, we investigated the protective efficiency of pretreatment of indobufen or aspirin combined with clopidogrel or ticagrelor (IACT) on cerebral...

Cite
Li F, Xu D, Hou K, et al. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021;16(4):835-853doi: 10.1007/s11481-020-09978-9.
Li, F., Xu, D., Hou, K., Gou, X., Lv, N., Fang, W., & Li, Y. (2021). Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 16(4), 835-853. https://doi.org/10.1007/s11481-020-09978-9
Li, Fengyang, et al. "Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology vol. 16,4 (2021): 835-853. doi: https://doi.org/10.1007/s11481-020-09978-9
Li F, Xu D, Hou K, Gou X, Lv N, Fang W, Li Y. Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke. J Neuroimmune Pharmacol. 2021 Dec;16(4):835-853. doi: 10.1007/s11481-020-09978-9. Epub 2021 Jan 29. PMID: 33512659.
Copy Download .nbib Format: NLM
Showing 1 to 11 of 11 entries