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Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice.

Molecular medicine (Cambridge, Mass.)

Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ.
PMID: 26322849
Mol Med. 2015 Nov;21(1):702-708. doi: 10.2119/molmed.2015.00142. Epub 2015 Aug 17.

Type 1 diabetes in mice is characterized by autoimmune destruction of insulin-producing pancreatic β-cells. Disease pathogenesis involves invasion of pancreatic islets by immune cells, including macrophages and T cells, and production of antibodies to self-antigens, including insulin. Activation of...

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Hanes WM, Olofsson PS, Kwan K, et al. Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Mol Med. 2015;21(1):702-708doi: 10.2119/molmed.2015.00142.
Hanes, W. M., Olofsson, P. S., Kwan, K., Hudson, L. K., Chavan, S. S., Pavlov, V. A., & Tracey, K. J. (2015). Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Molecular medicine (Cambridge, Mass.), 21(1), 702-708. https://doi.org/10.2119/molmed.2015.00142
Hanes, William M, et al. "Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice." Molecular medicine (Cambridge, Mass.) vol. 21,1 (2015): 702-708. doi: https://doi.org/10.2119/molmed.2015.00142
Hanes WM, Olofsson PS, Kwan K, Hudson LK, Chavan SS, Pavlov VA, Tracey KJ. Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice. Mol Med. 2015 Nov;21(1):702-708. doi: 10.2119/molmed.2015.00142. Epub 2015 Aug 17. PMID: 26322849; PMCID: PMC4749496.
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A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens.

Veterinary medicine international

Reese KA, Lupfer C, Johnson RC, Mitev GM, Mullen VM, Geller BL, Pastey M.
PMID: 23766929
Vet Med Int. 2013;2013:316926. doi: 10.1155/2013/316926. Epub 2013 May 22.

A cost-effective and efficacious influenza vaccine for use in commercial poultry farms would help protect against avian influenza outbreaks. Current influenza vaccines for poultry are expensive and subtype specific, and therefore there is an urgent need to develop a...

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Reese KA, Lupfer C, Johnson RC, et al. A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens. Vet Med Int. 2013;2013:316926doi: 10.1155/2013/316926.
Reese, K. A., Lupfer, C., Johnson, R. C., Mitev, G. M., Mullen, V. M., Geller, B. L., & Pastey, M. (2013). A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens. Veterinary medicine international, 2013316926. https://doi.org/10.1155/2013/316926
Reese, Kaleb A, et al. "A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens." Veterinary medicine international vol. 2013 (2013): 316926. doi: https://doi.org/10.1155/2013/316926
Reese KA, Lupfer C, Johnson RC, Mitev GM, Mullen VM, Geller BL, Pastey M. A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens. Vet Med Int. 2013;2013:316926. doi: 10.1155/2013/316926. Epub 2013 May 22. PMID: 23766929; PMCID: PMC3674685.
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Malignancy: Idiotypic Immune Targeting of Multiple Myeloma.

Hematology (Amsterdam, Netherlands)

Lim SH, Wen YJ, Ling M.
PMID: 11399589
Hematology. 2000;4(6):471-477.

Immunotherapy of malignant diseases remains a major therapeutic challenge. In multiple myeloma, interests have been focussed primarily on the targeting of the idiotypic protein since it represents one of the few tumor specific antigens. Various vaccination strategies have been...

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Lim SH, Wen YJ, Ling M. Malignancy: Idiotypic Immune Targeting of Multiple Myeloma. Hematology. 2000;4(6):471-477
Lim, S. H., Wen, Y. J., & Ling, M. (2000). Malignancy: Idiotypic Immune Targeting of Multiple Myeloma. Hematology (Amsterdam, Netherlands), 4(6), 471-477.
Lim, SEAH H., et al. "Malignancy: Idiotypic Immune Targeting of Multiple Myeloma." Hematology (Amsterdam, Netherlands) vol. 4,6 (2000): 471-477.
Lim SH, Wen YJ, Ling M. Malignancy: Idiotypic Immune Targeting of Multiple Myeloma. Hematology. 2000;4(6):471-477. PMID: 11399589.
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Inability of liver dendritic cells from mouse with experimental hepatitis to process and present specific antigens.

Hepatology research : the official journal of the Japan Society of Hepatology

Abe M, Akbar SM, Horiike N, Onji M.
PMID: 12787806
Hepatol Res. 2003 May;26(1):61-67. doi: 10.1016/s1386-6346(02)00333-9.

The functions of resident antigen-presenting cells (APC) may be compromised in inflammatory microenvironment of the host. However, little is known regarding the phenotype and function of the liver resident APC in this condition. This issue was addressed by evaluating...

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Abe M, Akbar SM, Horiike N, et al. Inability of liver dendritic cells from mouse with experimental hepatitis to process and present specific antigens. Hepatol Res. 2003;26(1):61-67doi: 10.1016/s1386-6346(02)00333-9.
Abe, M., Akbar, S. M., Horiike, N., & Onji, M. (2003). Inability of liver dendritic cells from mouse with experimental hepatitis to process and present specific antigens. Hepatology research : the official journal of the Japan Society of Hepatology, 26(1), 61-67. https://doi.org/10.1016/s1386-6346(02)00333-9
Abe, Masanori, et al. "Inability of liver dendritic cells from mouse with experimental hepatitis to process and present specific antigens." Hepatology research : the official journal of the Japan Society of Hepatology vol. 26,1 (2003): 61-67. doi: https://doi.org/10.1016/s1386-6346(02)00333-9
Abe M, Akbar SM, Horiike N, Onji M. Inability of liver dendritic cells from mouse with experimental hepatitis to process and present specific antigens. Hepatol Res. 2003 May;26(1):61-67. doi: 10.1016/s1386-6346(02)00333-9. PMID: 12787806.
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Flow immunoassay of trinitrophenol based on a surface plasmon resonance sensor using a one-pot immunoreaction with a high molecular weight conjugate.

Talanta

Kobayashi M, Sato M, Li Y, Soh N, Nakano K, Toko K, Miura N, Matsumoto K, Hemmi A, Asano Y, Imato T.
PMID: 18970305
Talanta. 2005 Dec 15;68(2):198-206. doi: 10.1016/j.talanta.2005.06.060. Epub 2005 Aug 10.

A surface plasmon resonance (SPR) immunosensor based on a competitive immunoreaction for the determination of trinitrophenol (TNP) is described. A goat anti-mouse IgG (1st antibody), which recognizes an Fc moiety of an antibody, was immobilized on a gold film...

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Kobayashi M, Sato M, Li Y, et al. Flow immunoassay of trinitrophenol based on a surface plasmon resonance sensor using a one-pot immunoreaction with a high molecular weight conjugate. Talanta. 2005;68(2):198-206doi: 10.1016/j.talanta.2005.06.060.
Kobayashi, M., Sato, M., Li, Y., Soh, N., Nakano, K., Toko, K., Miura, N., Matsumoto, K., Hemmi, A., Asano, Y., & Imato, T. (2005). Flow immunoassay of trinitrophenol based on a surface plasmon resonance sensor using a one-pot immunoreaction with a high molecular weight conjugate. Talanta, 68(2), 198-206. https://doi.org/10.1016/j.talanta.2005.06.060
Kobayashi, Masatoshi, et al. "Flow immunoassay of trinitrophenol based on a surface plasmon resonance sensor using a one-pot immunoreaction with a high molecular weight conjugate." Talanta vol. 68,2 (2005): 198-206. doi: https://doi.org/10.1016/j.talanta.2005.06.060
Kobayashi M, Sato M, Li Y, Soh N, Nakano K, Toko K, Miura N, Matsumoto K, Hemmi A, Asano Y, Imato T. Flow immunoassay of trinitrophenol based on a surface plasmon resonance sensor using a one-pot immunoreaction with a high molecular weight conjugate. Talanta. 2005 Dec 15;68(2):198-206. doi: 10.1016/j.talanta.2005.06.060. Epub 2005 Aug 10. PMID: 18970305.
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Preparation and characterization of a polyclonal antibody from rabbit for detection of trinitrotoluene by a surface plasmon resonance biosensor.

Talanta

Matsumoto K, Torimaru A, Ishitobi S, Sakai T, Ishikawa H, Toko K, Miura N, Imato T.
PMID: 18970322
Talanta. 2005 Dec 15;68(2):305-11. doi: 10.1016/j.talanta.2005.08.054. Epub 2005 Sep 21.

A polyclonal antibody against trinitrophenyl (TNP) derivatives was raised in rabbit, and the antibody was applied to detection of trinitrotoluene (TNT) using a surface plasmon resonance (SPR) biosensor. TNP-keyhole limpet hemocyanine (TNP-KLH) conjugate was injected into a rabbit, and...

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Matsumoto K, Torimaru A, Ishitobi S, et al. Preparation and characterization of a polyclonal antibody from rabbit for detection of trinitrotoluene by a surface plasmon resonance biosensor. Talanta. 2005;68(2):305-11doi: 10.1016/j.talanta.2005.08.054.
Matsumoto, K., Torimaru, A., Ishitobi, S., Sakai, T., Ishikawa, H., Toko, K., Miura, N., & Imato, T. (2005). Preparation and characterization of a polyclonal antibody from rabbit for detection of trinitrotoluene by a surface plasmon resonance biosensor. Talanta, 68(2), 305-11. https://doi.org/10.1016/j.talanta.2005.08.054
Matsumoto, Kiyoshi, et al. "Preparation and characterization of a polyclonal antibody from rabbit for detection of trinitrotoluene by a surface plasmon resonance biosensor." Talanta vol. 68,2 (2005): 305-11. doi: https://doi.org/10.1016/j.talanta.2005.08.054
Matsumoto K, Torimaru A, Ishitobi S, Sakai T, Ishikawa H, Toko K, Miura N, Imato T. Preparation and characterization of a polyclonal antibody from rabbit for detection of trinitrotoluene by a surface plasmon resonance biosensor. Talanta. 2005 Dec 15;68(2):305-11. doi: 10.1016/j.talanta.2005.08.054. Epub 2005 Sep 21. PMID: 18970322.
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Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [Overview of a Workshop Session at the 45th Annual Meeting of the Society of Toxicology (SOT) March 5-9, 2006 San Diego, CA].

Journal of immunotoxicology

Herzyk DJ, Holsapple M.
PMID: 18958722
J Immunotoxicol. 2007 Apr;4(2):143-7. doi: 10.1080/15476910701337308.

Increased expectations from a number of regulatory agencies, e.g., Environmental Protection Agency (EPA), Food and Drug Administration (FDA), European Medicines Agency (EMEA), and the Ministry of Health, Labour and Welfare (MHLW) of Japan, call for the evaluation of potential...

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Herzyk DJ, Holsapple M. Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [Overview of a Workshop Session at the 45th Annual Meeting of the Society of Toxicology (SOT) March 5-9, 2006 San Diego, CA]. J Immunotoxicol. 2007;4(2):143-7doi: 10.1080/15476910701337308.
Herzyk, D. J., & Holsapple, M. (2007). Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [Overview of a Workshop Session at the 45th Annual Meeting of the Society of Toxicology (SOT) March 5-9, 2006 San Diego, CA]. Journal of immunotoxicology, 4(2), 143-7. https://doi.org/10.1080/15476910701337308
Herzyk, Danuta J, and Holsapple, Michael. "Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [Overview of a Workshop Session at the 45th Annual Meeting of the Society of Toxicology (SOT) March 5-9, 2006 San Diego, CA]." Journal of immunotoxicology vol. 4,2 (2007): 143-7. doi: https://doi.org/10.1080/15476910701337308
Herzyk DJ, Holsapple M. Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [Overview of a Workshop Session at the 45th Annual Meeting of the Society of Toxicology (SOT) March 5-9, 2006 San Diego, CA]. J Immunotoxicol. 2007 Apr;4(2):143-7. doi: 10.1080/15476910701337308. PMID: 18958722.
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T-dependent antigen response (TDAR) tests: meta-analysis of results generated across multiple laboratories.

Journal of immunotoxicology

Bugelski PJ, Kim C.
PMID: 18958725
J Immunotoxicol. 2007 Apr;4(2):159-64. doi: 10.1080/15476910701337126.

The primary T-cell-dependent antibody response (TDAR) to antigens is widely used as a functional test in immunotoxicology. TDAR assays can be performed using different antigens, e.g., sheep red blood cells (SRBC) and keyhole limpet hemocyanin (KLH) are presently utilized...

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Bugelski PJ, Kim C. T-dependent antigen response (TDAR) tests: meta-analysis of results generated across multiple laboratories. J Immunotoxicol. 2007;4(2):159-64doi: 10.1080/15476910701337126.
Bugelski, P. J., & Kim, C. (2007). T-dependent antigen response (TDAR) tests: meta-analysis of results generated across multiple laboratories. Journal of immunotoxicology, 4(2), 159-64. https://doi.org/10.1080/15476910701337126
Bugelski, Peter J, and Kim, Carin. "T-dependent antigen response (TDAR) tests: meta-analysis of results generated across multiple laboratories." Journal of immunotoxicology vol. 4,2 (2007): 159-64. doi: https://doi.org/10.1080/15476910701337126
Bugelski PJ, Kim C. T-dependent antigen response (TDAR) tests: meta-analysis of results generated across multiple laboratories. J Immunotoxicol. 2007 Apr;4(2):159-64. doi: 10.1080/15476910701337126. PMID: 18958725.
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Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients.

Journal of translational medicine

Ridolfi R, Petrini M, Fiammenghi L, Stefanelli M, Ridolfi L, Ballardini M, Migliori G, Riccobon A.
PMID: 16914047
J Transl Med. 2006 Aug 16;4:36. doi: 10.1186/1479-5876-4-36.

BACKGROUND: We present our experience of therapeutic vaccination using dendritic cells (DC) pulsed with autologous tumor antigens in patients with advanced melanoma.METHODS: Twenty-one pretreated advanced melanoma patients were vaccinated with autologous DC pulsed with 100 microg/ml of autologous-tumor-lysate (ATL)...

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Ridolfi R, Petrini M, Fiammenghi L, et al. Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients. J Transl Med. 2006;4:36doi: 10.1186/1479-5876-4-36.
Ridolfi, R., Petrini, M., Fiammenghi, L., Stefanelli, M., Ridolfi, L., Ballardini, M., Migliori, G., & Riccobon, A. (2006). Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients. Journal of translational medicine, 436. https://doi.org/10.1186/1479-5876-4-36
Ridolfi, Ruggero, et al. "Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients." Journal of translational medicine vol. 4 (2006): 36. doi: https://doi.org/10.1186/1479-5876-4-36
Ridolfi R, Petrini M, Fiammenghi L, Stefanelli M, Ridolfi L, Ballardini M, Migliori G, Riccobon A. Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients. J Transl Med. 2006 Aug 16;4:36. doi: 10.1186/1479-5876-4-36. PMID: 16914047; PMCID: PMC1562447.
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Autoimmunization of ewes against pregnancy-associated glycoproteins does not interfere with the establishment and maintenance of pregnancy.

Animal : an international journal of animal bioscience

Egen TE, Ealy AD, Landon LA, Roberts RM, Green JA.
PMID: 22444772
Animal. 2009 Jun;3(6):850-7. doi: 10.1017/S1751731109004145.

Pregnancy-associated glycoproteins (PAGs) are a large grouping of placental proteins that belong to the aspartic peptidase gene family. Although useful to detect pregnancy in ruminant species, the function of these molecules is unclear. Several PAGs expressed by trophoblast binucleate...

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Egen TE, Ealy AD, Landon LA, et al. Autoimmunization of ewes against pregnancy-associated glycoproteins does not interfere with the establishment and maintenance of pregnancy. Animal. 2009;3(6):850-7doi: 10.1017/S1751731109004145.
Egen, T. E., Ealy, A. D., Landon, L. A., Roberts, R. M., & Green, J. A. (2009). Autoimmunization of ewes against pregnancy-associated glycoproteins does not interfere with the establishment and maintenance of pregnancy. Animal : an international journal of animal bioscience, 3(6), 850-7. https://doi.org/10.1017/S1751731109004145
Egen, T E, et al. "Autoimmunization of ewes against pregnancy-associated glycoproteins does not interfere with the establishment and maintenance of pregnancy." Animal : an international journal of animal bioscience vol. 3,6 (2009): 850-7. doi: https://doi.org/10.1017/S1751731109004145
Egen TE, Ealy AD, Landon LA, Roberts RM, Green JA. Autoimmunization of ewes against pregnancy-associated glycoproteins does not interfere with the establishment and maintenance of pregnancy. Animal. 2009 Jun;3(6):850-7. doi: 10.1017/S1751731109004145. PMID: 22444772.
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Development of a simple and rapid elisa of urinary cotinine for epidemiological application.

Environmental health and preventive medicine

Yoshioka N, Dohi Y, Yonemasu K.
PMID: 21432502
Environ Health Prev Med. 1998 Apr;3(1):12-6. doi: 10.1007/BF02931233.

Highly stereospecific polyclonal antibodies (anti-CN) to cotinine (CN), a major metabolite of nicotine, were prepared from rabbit antisera to CN-linked keyhole limpet hemocyanin (KLH) by removing the antibodies to KLH and to its binding regions of CN. This was...

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Yoshioka N, Dohi Y, Yonemasu K. Development of a simple and rapid elisa of urinary cotinine for epidemiological application. Environ Health Prev Med. 1998;3(1):12-6doi: 10.1007/BF02931233.
Yoshioka, N., Dohi, Y., & Yonemasu, K. (1998). Development of a simple and rapid elisa of urinary cotinine for epidemiological application. Environmental health and preventive medicine, 3(1), 12-6. https://doi.org/10.1007/BF02931233
Yoshioka, N, et al. "Development of a simple and rapid elisa of urinary cotinine for epidemiological application." Environmental health and preventive medicine vol. 3,1 (1998): 12-6. doi: https://doi.org/10.1007/BF02931233
Yoshioka N, Dohi Y, Yonemasu K. Development of a simple and rapid elisa of urinary cotinine for epidemiological application. Environ Health Prev Med. 1998 Apr;3(1):12-6. doi: 10.1007/BF02931233. PMID: 21432502; PMCID: PMC2723266.
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A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle.

Angewandte Chemie (International ed. in English)

Ragupathi G, Slovin SF, Adluri S, Sames D, Kim IJ, Kim HM, Spassova M, Bornmann WG, Lloyd KO, Scher HI, Livingston PO, Danishefsky SJ.
PMID: 29711780
Angew Chem Int Ed Engl. 1999 Feb 15;38(4):563-566. doi: 10.1002/(SICI)1521-3773(19990215)38:4<563::AID-ANIE563>3.0.CO;2-3.

Human trials on the globo H carbohydrate vaccine (see picture, KLH=the carrier protein keyhole limpet hemocyanin) show that it produces strong IgM, and in some cases IgG, responses in patients with progressive and recurrent prostate cancer. Furthermore, these antibodies...

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Ragupathi G, Slovin SF, Adluri S, et al. A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle. Angew Chem Int Ed Engl. 1999;38(4):563-566doi: 10.1002/(SICI)1521-3773(19990215)38:4<563::AID-ANIE563>3.0.CO;2-3.
Ragupathi, G., Slovin, S. F., Adluri, S., Sames, D., Kim, I. J., Kim, H. M., Spassova, M., Bornmann, W. G., Lloyd, K. O., Scher, H. I., Livingston, P. O., & Danishefsky, S. J. (1999). A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle. Angewandte Chemie (International ed. in English), 38(4), 563-566. https://doi.org/10.1002/(SICI)1521-3773(19990215)38:4<563::AID-ANIE563>3.0.CO;2-3
Ragupathi, Govindaswami, et al. "A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle." Angewandte Chemie (International ed. in English) vol. 38,4 (1999): 563-566. doi: https://doi.org/10.1002/(SICI)1521-3773(19990215)38:4<563::AID-ANIE563>3.0.CO;2-3
Ragupathi G, Slovin SF, Adluri S, Sames D, Kim IJ, Kim HM, Spassova M, Bornmann WG, Lloyd KO, Scher HI, Livingston PO, Danishefsky SJ. A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused Humoral Response in Prostate Cancer Patients: A Proof of Principle. Angew Chem Int Ed Engl. 1999 Feb 15;38(4):563-566. doi: 10.1002/(SICI)1521-3773(19990215)38:4<563::AID-ANIE563>3.0.CO;2-3. PMID: 29711780.
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Showing 1 to 12 of 101 entries