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Effect of ursodeoxycholate-3,7-disulfate on biliary excretion of lithocholate-3-O-glucuronide in Eisai hyperbilirubinemic rat (EHBR).

Hepatology research : the official journal of the Japan Society of Hepatology

Hasegawa Y, Takikawa H.
PMID: 12191677
Hepatol Res. 2002 Aug;23(4):296. doi: 10.1016/s1386-6346(01)00188-7.

Biliary excretion of lithocholate-3-O-glucuronide and ursodeoxycholate-3,7-disulfate is markedly impaired in EHBR, in which the multidrug resistance protein 2 (Mrp2), a major ATP-dependent canalicular organic anion transporter, is impaired. We previously reported that biliary excretion of lithocholate-3-sulfate was enhanced by...

Effect of genipin on cholestasis induced by estradiol-17beta-glucuronide and lithocholate-3-O-glucuornide in rats.

Hepatology research : the official journal of the Japan Society of Hepatology

Goto H, Takikawa H.
PMID: 20374298
Hepatol Res. 2010 May;40(5):524-9. doi: 10.1111/j.1872-034X.2010.00630.x. Epub 2010 Mar 30.

AIM: Genipin is reported to stimulate the insertion of multidrug resistance protein 2 (Mrp2) in the bile canalicular membrane, thereby causing choleresis by the increased the biliary excretion of glutathione, which has been considered to be a substrate of...

Showing 1 to 2 of 2 entries