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Showing 1 to 4 of 4 entries
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Bioinformatic Analysis of Leishmania donovani Long-Chain Fatty Acid-CoA Ligase as a Novel Drug Target.

Molecular biology international

Kaur J, Tiwari R, Kumar A, Singh N.
PMID: 22091399
Mol Biol Int. 2011;2011:278051. doi: 10.4061/2011/278051. Epub 2011 Jul 19.

Fatty acyl-CoA synthetase (fatty acid: CoA ligase, AMP-forming; (EC 6.2.1.3)) catalyzes the formation of fatty acyl-CoA by a two-step process that proceeds through the hydrolysis of pyrophosphate. Fatty acyl-CoA represents bioactive compounds that are involved in protein transport, enzyme...

Comparative proteomics elucidates the dynamics of ovarian development in the Chinese mitten crab Eriocheir sinensis.

Comparative biochemistry and physiology. Part D, Genomics & proteomics

Feng QM, Liu MM, Cheng YX, Wu XG.
PMID: 34333232
Comp Biochem Physiol Part D Genomics Proteomics. 2021 Dec;40:100878. doi: 10.1016/j.cbd.2021.100878. Epub 2021 Jul 08.

Ovarian development is a complex physiological process for crustacean reproduction that is divided into the oogonium proliferation stage, endogenous vitellogenic stage, exogenous vitellogenic stage, and oocyte maturation stage. Proteomics analysis offers a feasible approach to reveal the proteins involved...

Homozygous and heterozygous GH transgenesis alters fatty acid composition and content in the liver of Amago salmon (Oncorhynchus masou ishikawae).

Biology open

Sugiyama M, Takenaga F, Kitani Y, Yamamoto G, Okamoto H, Masaoka T, Araki K, Nagoya H, Mori T.
PMID: 23213381
Biol Open. 2012 Oct 15;1(10):1035-42. doi: 10.1242/bio.20121263. Epub 2012 Aug 21.

Growth hormone (GH) transgenic Amago (Oncorhynchus masou ishikawae), containing the sockeye GH1 gene fused with metallothionein-B promoter from the same species, were generated and the physiological condition through lipid metabolism compared among homozygous (Tg/Tg) and heterozygous GH transgenic (Tg/+)...

Deficient Chaperone-Mediated Autophagy Promotes Lipid Accumulation in Macrophage.

Journal of cardiovascular translational research

Qiao L, Wang HF, Xiang L, Ma J, Zhu Q, Xu D, Zheng H, Peng JQ, Zhang S, Lu HX, Chen WQ, Zhang Y.
PMID: 32285315
J Cardiovasc Transl Res. 2021 Aug;14(4):661-669. doi: 10.1007/s12265-020-09986-3. Epub 2020 Apr 13.

Chaperone-mediated autophagy (CMA) serves as a critical upstream regulator of lipophagy and lipid metabolism in hepatocyte. However, the role of CMA in lipid metabolism of macrophage, the typical component of atherosclerotic plaque, remains unclear. In our study, LAMP-2A (L2A,...

Showing 1 to 4 of 4 entries