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Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues.

Pharmaceutical research

Ensing K, de Zeeuw RA.
PMID: 24271831
Pharm Res. 1986 Dec;3(6):327-32. doi: 10.1023/A:1016379806395.

A number of corresponding tertiary and quaternary anticholinergic analogues were examined for their ability to inhibit specific (3)H-dexetimide binding to calf brain muscarinic receptors. In all cases the tertiary antagonists (except pirenzepine) showed steep and monophasic inhibition curves, whereas...

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Ensing K, de Zeeuw RA. Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues. Pharm Res. 1986;3(6):327-32doi: 10.1023/A:1016379806395.
Ensing, K., & de Zeeuw, R. A. (1986). Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues. Pharmaceutical research, 3(6), 327-32. https://doi.org/10.1023/A:1016379806395
Ensing, K, and de Zeeuw, R A. "Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues." Pharmaceutical research vol. 3,6 (1986): 327-32. doi: https://doi.org/10.1023/A:1016379806395
Ensing K, de Zeeuw RA. Different behavior toward muscarinic receptor binding between quaternary anticholinergics and their tertiary analogues. Pharm Res. 1986 Dec;3(6):327-32. doi: 10.1023/A:1016379806395. PMID: 24271831.
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The properties of cholinergic muscarinic receptor sites from bovine atria reconstituted after solubilization.

Neurochemistry international

Santiago Aguilar J, De Robertis E.
PMID: 20501171
Neurochem Int. 1987;11(3):273-82. doi: 10.1016/0197-0186(87)90046-5.

We have previously shown that the digitonin-cholate solubilization of the muscarinic receptor from bovine atrial membranes disrupts the heterogeneity of carbamylcholine binding sites and their modulation by guanine nucleotides. Polyethylene glycol precipitation of the detergent extract restores these properties,...

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Santiago Aguilar J, De Robertis E. The properties of cholinergic muscarinic receptor sites from bovine atria reconstituted after solubilization. Neurochem Int. 1987;11(3):273-82doi: 10.1016/0197-0186(87)90046-5.
Santiago Aguilar, J., & De Robertis, E. (1987). The properties of cholinergic muscarinic receptor sites from bovine atria reconstituted after solubilization. Neurochemistry international, 11(3), 273-82. https://doi.org/10.1016/0197-0186(87)90046-5
Santiago Aguilar, J, and De Robertis, E. "The properties of cholinergic muscarinic receptor sites from bovine atria reconstituted after solubilization." Neurochemistry international vol. 11,3 (1987): 273-82. doi: https://doi.org/10.1016/0197-0186(87)90046-5
Santiago Aguilar J, De Robertis E. The properties of cholinergic muscarinic receptor sites from bovine atria reconstituted after solubilization. Neurochem Int. 1987;11(3):273-82. doi: 10.1016/0197-0186(87)90046-5. PMID: 20501171.
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Spectrophotometric determination of strychnine and methylatropine by extraction with tetrabromophenolphthalein ethyl ester.

Talanta

Tsubouchi M, Sakai T, Watake T, Kanazawa K, Tanaka M.
PMID: 18961259
Talanta. 1973 Feb;20(2):222-4. doi: 10.1016/0039-9140(73)80271-1.

A new application of monoacidic dyes is reported for the determination of strychnine and methylatropine. The method is based on solvent extraction into 1,2-dichloroethane of the ion-pair or addition compound formed between tetrabromophenolphthalein ethyl ester and quaternary ammonium salts...

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Tsubouchi M, Sakai T, Watake T, et al. Spectrophotometric determination of strychnine and methylatropine by extraction with tetrabromophenolphthalein ethyl ester. Talanta. 1973;20(2):222-4doi: 10.1016/0039-9140(73)80271-1.
Tsubouchi, M., Sakai, T., Watake, T., Kanazawa, K., & Tanaka, M. (1973). Spectrophotometric determination of strychnine and methylatropine by extraction with tetrabromophenolphthalein ethyl ester. Talanta, 20(2), 222-4. https://doi.org/10.1016/0039-9140(73)80271-1
Tsubouchi, M, et al. "Spectrophotometric determination of strychnine and methylatropine by extraction with tetrabromophenolphthalein ethyl ester." Talanta vol. 20,2 (1973): 222-4. doi: https://doi.org/10.1016/0039-9140(73)80271-1
Tsubouchi M, Sakai T, Watake T, Kanazawa K, Tanaka M. Spectrophotometric determination of strychnine and methylatropine by extraction with tetrabromophenolphthalein ethyl ester. Talanta. 1973 Feb;20(2):222-4. doi: 10.1016/0039-9140(73)80271-1. PMID: 18961259.
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Methylatropine blocks the central effects of cholinergic antagonists.

Behavioural pharmacology

Smith RD, Grzelak ME, Coffin VL.
PMID: 11224265
Behav Pharmacol. 1994 Apr;5(2):167-175. doi: 10.1097/00008877-199404000-00008.

These studies were conducted in order to establish the dose dependency and relative peripheral versus central activity of four prototypical cholinergic antagonists on the rodent passive avoidance response, a widely used animal model of retention. Subcutaneous administration of 0.1...

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Smith RD, Grzelak ME, Coffin VL. Methylatropine blocks the central effects of cholinergic antagonists. Behav Pharmacol. 1994;5(2):167-175doi: 10.1097/00008877-199404000-00008.
Smith, R. D., Grzelak, M. E., & Coffin, V. L. (1994). Methylatropine blocks the central effects of cholinergic antagonists. Behavioural pharmacology, 5(2), 167-175. https://doi.org/10.1097/00008877-199404000-00008
Smith, R.D., et al. "Methylatropine blocks the central effects of cholinergic antagonists." Behavioural pharmacology vol. 5,2 (1994): 167-175. doi: https://doi.org/10.1097/00008877-199404000-00008
Smith RD, Grzelak ME, Coffin VL. Methylatropine blocks the central effects of cholinergic antagonists. Behav Pharmacol. 1994 Apr;5(2):167-175. doi: 10.1097/00008877-199404000-00008. PMID: 11224265.
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Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats.

Frontiers in physiology

Klippel BF, Duemke LB, Leal MA, Friques AG, Dantas EM, Dalvi RF, Gava AL, Pereira TM, Andrade TU, Meyrelles SS, Campagnaro BP, Vasquez EC.
PMID: 27375490
Front Physiol. 2016 Jun 07;7:211. doi: 10.3389/fphys.2016.00211. eCollection 2016.

AIMS: It has been previously shown that the probiotic kefir (a symbiotic matrix containing acid bacteria and yeasts) attenuated the hypertension and the endothelial dysfunction in spontaneously hypertensive rats (SHR). In the present study, the effect of chronic administration...

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Klippel BF, Duemke LB, Leal MA, et al. Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats. Front Physiol. 2016;7:211doi: 10.3389/fphys.2016.00211.
Klippel, B. F., Duemke, L. B., Leal, M. A., Friques, A. G., Dantas, E. M., Dalvi, R. F., Gava, A. L., Pereira, T. M., Andrade, T. U., Meyrelles, S. S., Campagnaro, B. P., & Vasquez, E. C. (2016). Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats. Frontiers in physiology, 7211. https://doi.org/10.3389/fphys.2016.00211
Klippel, Brunella F, et al. "Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats." Frontiers in physiology vol. 7 (2016): 211. doi: https://doi.org/10.3389/fphys.2016.00211
Klippel BF, Duemke LB, Leal MA, Friques AG, Dantas EM, Dalvi RF, Gava AL, Pereira TM, Andrade TU, Meyrelles SS, Campagnaro BP, Vasquez EC. Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats. Front Physiol. 2016 Jun 07;7:211. doi: 10.3389/fphys.2016.00211. eCollection 2016. PMID: 27375490; PMCID: PMC4895057.
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Showing 1 to 5 of 5 entries