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Enhancement of oral bioavailability and anti-hyperuricemic activity of aloe emodin via novel Soluplus®-glycyrrhizic acid mixed micelle system.

Drug delivery and translational research

Shi F, Chen L, Wang Y, Liu J, Adu-Frimpong M, Ji H, Toreniyazov E, Wang Q, Yu J, Xu X.
PMID: 33860450
Drug Deliv Transl Res. 2021 Apr 15; doi: 10.1007/s13346-021-00969-8. Epub 2021 Apr 15.

The objective of this study was to fabricate a novel drug delivery system using Soluplus® (polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer) and glycyrrhizic acid to improve solubility, bioavailability, and anti-hyperuricemic activity of aloe emodin (AE). The AE-loaded mixed micelles...

Showing 1 to 1 of 1 entries