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Showing 1 to 12 of 20 entries
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Role of Dopaminergic D2 Receptors in the Regulation of Glutamic Acid Decarboxylase Messenger RNA in the Striatum of the Rat.

The European journal of neuroscience

Caboche J, Vernier P, Rogard M, Julien JF, Mallet J, Besson MJ.
PMID: 12106353
Eur J Neurosci. 1992;4(5):438-447. doi: 10.1111/j.1460-9568.1992.tb00894.x.

Levels of messenger RNA (mRNA) encoding glutamic acid decarboxylase (GAD) and preproenkephalin (PPE) were measured by Northern blot and in situ hybridization analyses in the striatum of the rat, after chronic injections of two neuroleptics, sulpiride and haloperidol. The...

The effect of social stress on hippocampal gene expression.

Molecular and cellular neurosciences

Chao HM, Blanchard DC, Blanchard RJ, McEwen BS, Sakai RR.
PMID: 19912962
Mol Cell Neurosci. 1993 Dec;4(6):543-8. doi: 10.1006/mcne.1993.1067.

The housing of male and female rats in a visible burrow system in which a dominance hierarchy is established and interactions between animals can be monitored provides an effective method by which the behavioral and neuroendocrine effects of social...

Proopiomelanocortin, Preproenkephalin-A and Preprocholecystokinin mRNA in the Hypothalamus of CCI-Treated Rats.

Journal of neuroendocrinology

Brini A, Morghen C, Bianchi M, Rovati LC, Panerai AE.
PMID: 19210434
J Neuroendocrinol. 1989 Aug 01;1(4):235-6. doi: 10.1111/j.1365-2826.1989.tb00109.x.

It has previously been shown that beta-endorphin (BE) and cholecystokinin (CCK) concentrations decrease in brain areas of rats or humans affected by severe liver disease (SLD). We now report the increase of proopiomelanocortin (POMC) and preprocholecystokinin mRNA in the...

Viral Vectors for Gene Delivery and Expression in the CNS.

Methods (San Diego, Calif.)

Kaplitt MG, Pfaff DW.
PMID: 8954846
Methods. 1996 Dec;10(3):343-50. doi: 10.1006/meth.1996.0112.

Viral vectors have emerged as an important tool for manipulating gene expression in the adult mammalian brain. The adult brain is composed largely of nondividing cells, and therefore DNA viruses have become the vehicle of choice for neurobiologists interested...

Cholinergic agonist-induced binding of adrenomedullary nuclear proteins to the rat preproenkephalin promoter.

Molecular and cellular neurosciences

La Gamma EF, Decristofaro J, Weisinger G.
PMID: 19912837
Mol Cell Neurosci. 1991 Dec;2(6):517-25. doi: 10.1016/1044-7431(91)90019-k.

Cholinergic receptors are well-recognized modulators of transmitter release and biosynthesis with newly identified actions mediated through trans-acting DNA binding proteins affecting gene expression at cis-acting regulatory elements. In the case of the rat preproenkephalin (ppEnk) gene, we have identified...

Intrahippocampal NMDA Administration Alters Fos, Fos-Related Antigens, and Opioid Peptide Immunoreactivity and mRNA in Rats.

Molecular and cellular neurosciences

Helton TE, McGinty JF.
PMID: 19912939
Mol Cell Neurosci. 1993 Aug;4(4):319-34. doi: 10.1006/mcne.1993.1042.

In this study, the glutamate receptor agonist, NMDA, was used to induce epileptic seizures in order to compare the expression of the immediate early gene (IEG) products, Fos and Fos-related antigens (Fras), with the opioid peptides, dynorphin (DYN) and...

Time- and region-dependent effect of adrenalectomy on neuropeptide gene expression in rat hippocampus and striatum.

Molecular and cellular neurosciences

Iglesias T, Verbeeck MA, De Kloet RE, Sutanto W, Fuentes J, Burbach JP.
PMID: 19912833
Mol Cell Neurosci. 1991 Dec;2(6):485-90. doi: 10.1016/1044-7431(91)90015-g.

Seven days after removal of the adrenals in rats, the messenger RNA levels of preproenkephalin (ENK), preprodynorphin (DYN), cholecystokinin (CCK), and neuropeptide Y (NPY) were measured in hippocampus, striatum, and hypothalamus. Adrenalectomy (ADX) in the morning, when endogenous corticosterone...

The Expressing Patterns of Opioid Peptides, Anti-opioid Peptides and Their Receptors in the Central Nervous System Are Involved in Electroacupuncture Tolerance in Goats.

Frontiers in neuroscience

Wan J, Qiu Z, Ding Y, Nan S, Ding M.
PMID: 30618545
Front Neurosci. 2018 Dec 13;12:902. doi: 10.3389/fnins.2018.00902. eCollection 2018.

To investigate dynamic processes of enkephalin (ENK), cholecystokinin octapeptide (CCK-8), orphanin FQ (OFQ) and their receptors (μ opioid receptor, MOR; CCK B type receptor, CCKBR and opioid receptor-like 1 receptor, OPRL1) in the central nerve system (CNS) during electroacupuncture...

Regulation of Opioid Receptors by Their Endogenous Opioid Peptides.

Cellular and molecular neurobiology

Gupta A, Gullapalli S, Pan H, Ramos-Ortolaza DL, Hayward MD, Low MJ, Pintar JE, Devi LA, Gomes I.
PMID: 33389463
Cell Mol Neurobiol. 2021 Jul;41(5):1103-1118. doi: 10.1007/s10571-020-01015-w. Epub 2021 Jan 02.

Activation of μ, δ, and κ opioid receptors by endogenous opioid peptides leads to the regulation of many emotional and physiological responses. The three major endogenous opioid peptides, β-endorphin, enkephalins, and dynorphins result from the processing of three main...

What do we understand from clinical and mechanistic studies on acupuncture treatment for hypertension?.

Chinese medicine

Cheng L, Li P, Tjen-A-Looi SC, Longhurst JC.
PMID: 26628909
Chin Med. 2015 Nov 30;10:36. doi: 10.1186/s13020-015-0070-9. eCollection 2015.

The outcome of acupuncture on hypertension treatment is inconclusive. This study aims to evaluate the influence of acupuncture on hypertension, based on findings from mechanistic studies over the course of decades particularly those conducted at the University of California,...

The Role of BDNF/TrkB Signaling in Acute Amphetamine-Induced Locomotor Activity and Opioid Peptide Gene Expression in the Rat Dorsal Striatum.

Frontiers in systems neuroscience

McGinty JF, Bache AJ, Coleman NT, Sun WL.
PMID: 21811445
Front Syst Neurosci. 2011 Jul 21;5:60. doi: 10.3389/fnsys.2011.00060. eCollection 2011.

Exposure to psychostimulants increases brain-derived neurotrophic factor (BDNF) mRNA and protein levels in the cerebral cortex and subcortical structures. Because BDNF is co-localized with dopamine and glutamate in afferents to the striatum of rats, it may be co-released with...

Heme oxygenase-1 in the spinal cord plays crucial roles in the analgesic effects of pregabalin and gabapentin in a spared nerve-injury mouse model.

Neuroscience letters

Godai K, Moriyama T.
PMID: 34736722
Neurosci Lett. 2022 Jan 10;767:136310. doi: 10.1016/j.neulet.2021.136310. Epub 2021 Oct 29.

INTRODUCTION: Neuropathic pain remains one of the most intractable types of pain; although calcium channel αMETHODS: Neuropathic pain was induced by spared nerve injury (SNI) of the sciatic nerve. The mechanical threshold was tested using the von Frey filaments....

Showing 1 to 12 of 20 entries