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Showing 1 to 5 of 5 entries
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Methanolic extract of Cucumis melo attenuates ethylene glycol-induced nephrolithiasis in Wistar rats.

Urolithiasis

Afzal M, Alharbi KS, Alzarea SI, Quazi AM, Ameeduzzafar Zafar, Patel DM, Patel AB, Trivedi R, Kazmi I, Al-Abaasi FA.
PMID: 33835227
Urolithiasis. 2021 Aug;49(4):301-308. doi: 10.1007/s00240-021-01263-5. Epub 2021 Apr 09.

Evaluation of the effects of methanolic extract of Cucumis melo in ethylene glycol-induced nephrolithiasis on Wistar rats. 0.75% solution of ethylene glycol (EG) in payable water was given to produce nephrolithiasis on Wistar rats. The action of oral intake...

6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism.

ACS omega

Afzal M, Kazmi I, Quazi AM, Khan SA, Zafar A, Al-Abbasi FA, Imam F, Alharbi KS, Alzarea SI, Yadav N.
PMID: 35036685
ACS Omega. 2021 Dec 28;7(1):140-148. doi: 10.1021/acsomega.1c04155. eCollection 2022 Jan 11.

Anxiety and depression are among the major traumatic brain injury-induced psychiatric disorders in survivors. The present study was undertaken to investigate the beneficial effects of 6-Shogaol against depression-like behavior and anxiety, induced by traumatic brain injury (TBI), in mice....

Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Afzal M, Kazmi I, Alharbi KS, Quazi AM, Nadeem MS, Alotaibi NH, Ameeduzzafar, Alruwaili NK, Anwar F, Alenezi SK, Al-Sanea MM.
PMID: 32435143
Saudi Pharm J. 2020 May;28(5):615-620. doi: 10.1016/j.jsps.2020.03.014. Epub 2020 Apr 02.

OBJECTIVE: Researchers have confirmed that chronic administration of drugs at high doses causes genotoxicity which serve as first step in development of cancers. Apremilast, a phosphodiesterase-4 inhibitor is Food and Drug Administration (FDA) approved drug for Psoriatic Arthritis. The...

Comparison of benzodiazepine (BZ) receptor agonists in two rodent activity tests.

Journal of psychopharmacology (Oxford, England)

Bayley PJ, Bentley GD, Jackson A, Williamson D, Dawson GR.
PMID: 22302946
J Psychopharmacol. 1996 Jan;10(3):206-13. doi: 10.1177/026988119601000305.

The effects of four BZ receptor ligands in an operant test were compared with a rotarod test. In the operant test, rats were trained to pull a chain on a schedule that regulates the probability of delivery of food...

6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents.

Saudi journal of biological sciences

Afzal M, Kazmi I, Quazi AM, Ahmad A, Al-Abaasi FA, Imam F, Alharbi KS, Alzarea SI, Zafar A.
PMID: 34121880
Saudi J Biol Sci. 2021 Jun;28(6):3418-3423. doi: 10.1016/j.sjbs.2021.03.005. Epub 2021 Mar 14.

The 6-shogaol, is a flavanone type flavonoid that is abundant in citrus fruit and has a wide range of pharmacological effects. The present study attempted to evaluate the antiurolithic effect of 6-shogaol on ethylene glycol (EG) and ammonium chloride...

Showing 1 to 5 of 5 entries