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Ramatroban as a Novel Immunotherapy for COVID-19.

Journal of molecular and genetic medicine : an international journal of biomedical research

Gupta A, Kalantar-Zadeh K, Reddy ST.
PMID: 32952595
J Mol Genet Med. 2020;14(3). doi: 10.37421/jmgm.2020.14.457. Epub 2020 Jul 30.

SARS-CoV-2 virus suppresses host innate and adaptive immune responses, thereby allowing the virus to proliferate, and cause multiorgan failure, especially in the elderly. Respiratory viruses stimulate cyclooxygenase-2 (COX-2) to generate prostanoids including Prostaglandin D

Kidney in the net of acute and long-haul coronavirus disease 2019: a potential role for lipid mediators in causing renal injury and fibrosis.

Current opinion in nephrology and hypertension

Chiang KC, Imig JD, Kalantar-Zadeh K, Gupta A.
PMID: 34846312
Curr Opin Nephrol Hypertens. 2022 Jan 01;31(1):36-46. doi: 10.1097/MNH.0000000000000750.

PURPOSE OF REVIEW: Severe COVID-19 disease is often complicated by acute kidney injury (AKI), which may transition to chronic kidney disease (CKD). Better understanding of underlying mechanisms is important in advancing therapeutic approaches.RECENT FINDINGS: SARS-CoV-2-induced endothelial injury initiates platelet...

Showing 1 to 2 of 2 entries