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Showing 1 to 12 of 65 entries
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Assessment of vocation of rifabutin and rifapentine in replace of rifampcin in drug resistance leprosy patients: a molecular simulation study.

Molecular biology research communications

Mohanty PS, Naaz F, Bansal AK, Gupta UD.
PMID: 29071280
Mol Biol Res Commun. 2017 Sep;6(3):113-122. doi: 10.22099/mbrc.2017.4084.

The emergence of drug resistance in leprosy is a major hurdle in leprosy elimination programme. Although the problem of drug resistance is presently not acute, it is important that we collect data more systematically and monitor the trend carefully...

Comparison of Chinese and Western rifapentines and improvement of bioavailability by prior taking of various meals.

International journal of antimicrobial agents

Chan SL, Yew WW, Porter JH, McAdam KP, Allen BW, Dickinson JM, Ellard GA, Mitchison DA.
PMID: 18611569
Int J Antimicrob Agents. 1994;3(4):267-74. doi: 10.1016/0924-8579(94)90054-x.

Bioavailability was measured by rifapentine (RPE) serum concentrations and by the urinary ratio between RPE and creatinine, in specimens obtained 4-50 h after 600 mg RPE preceded by food. The bioavailabilities of RPEs manufactured in China and by a...

Prospects for Tuberculosis Elimination in the United States: Results of a Transmission Dynamic Model.

American journal of epidemiology

Menzies NA, Cohen T, Hill AN, Yaesoubi R, Galer K, Wolf E, Marks SM, Salomon JA.
PMID: 29762657
Am J Epidemiol. 2018 Sep 01;187(9):2011-2020. doi: 10.1093/aje/kwy094.

We estimated long-term tuberculosis (TB) trends in the US population and assessed prospects for TB elimination. We used a detailed simulation model allowing for changes in TB transmission, immigration, and other TB risk determinants. Five hypothetical scenarios were evaluated...

Potential inhibitors of SARS-cov-2 RNA dependent RNA polymerase protein: molecular docking, molecular dynamics simulations and MM-PBSA analyses.

Journal of biomolecular structure & dynamics

Elkarhat Z, Charoute H, Elkhattabi L, Barakat A, Rouba H.
PMID: 32873176
J Biomol Struct Dyn. 2022 Jan;40(1):361-374. doi: 10.1080/07391102.2020.1813628. Epub 2020 Sep 02.

The SARS-cov-2 RNA dependent RNA polymerase (nsp12) is a crucial viral enzyme that catalyzes the replication of RNA from RNA templates. The fixation of some ligands in the active site may alter the viral life cycle. The aim of...

Isolated hepatic tuberculosis associated with portal vein thrombosis and hepatitis B virus coinfection: A case report and review of the literature.

World journal of clinical cases

Zheng SM, Lin N, Tang SH, Yang JY, Wang HQ, Luo SL, Zhang Y, Mu D.
PMID: 34786418
World J Clin Cases. 2021 Oct 26;9(30):9310-9319. doi: 10.12998/wjcc.v9.i30.9310.

BACKGROUND: While tuberculosis (TB) itself is a common disease, isolated TB of the liver is a rare entity. Tubercular involvement of the liver is more commonly a part of a disseminated disease of the hepatic parenchyma. In contrast, isolated...

Targeting Non-Replicating .

International journal of molecular sciences

Egorova A, Salina EG, Makarov V.
PMID: 34948114
Int J Mol Sci. 2021 Dec 10;22(24). doi: 10.3390/ijms222413317.

Latent tuberculosis infection (LTBI) represents a major challenge to curing TB disease. Current guidelines for LTBI management include only three older drugs and their combinations-isoniazid and rifamycins (rifampicin and rifapentine). These available control strategies have little impact on latent...

In vitro Synergism of Six Antituberculosis Agents Against Drug-Resistant .

Infection and drug resistance

Ying R, Huang X, Gao Y, Wang J, Liu Y, Sha W, Yang H.
PMID: 34548797
Infect Drug Resist. 2021 Sep 14;14:3729-3736. doi: 10.2147/IDR.S322563. eCollection 2021.

BACKGROUND: Retreatment tuberculosis (TB) has become a major source of drug-resistant TB. In contrast to the combination of isoniazid (INH) and rifampicin (RIF), that of pasiniazid (Pa) and rifabutin (RFB) or rifapentine (RFP) appears to have better activity in...

Retraction: Isoniazid and Rifapentine Treatment Eradicates Persistent .

American journal of respiratory and critical care medicine

[No authors listed]
PMID: 33856282
Am J Respir Crit Care Med. 2021 Apr 15;203(8):1045. doi: 10.1164/rccm.v203retraction1.

No abstract available.

Does Isoniazid Preventive Therapy Provide Better Treatment Outcomes in HIV-Infected Individuals in Northern Ethiopia? A Retrospective Cohort Study.

AIDS research and treatment

Atey TM, Bitew H, Asgedom SW, Endrias A, Berhe DF.
PMID: 32411454
AIDS Res Treat. 2020 Jan 21;2020:7025738. doi: 10.1155/2020/7025738. eCollection 2020.

OBJECTIVES: Early antiretroviral therapy (ART), isoniazid preventive therapy (IPT), and isoniazid-rifapentine (3HP) are effective strategies for preventing tuberculosis (TB) among people living with HIV (PLHIV). The study aimed to determine the effect of IPT on the TB incidence, follow-up...

Potential inhibitors of SARS-cov-2 RNA dependent RNA polymerase protein: molecular docking, molecular dynamics simulations and MM-PBSA analyses.

Journal of biomolecular structure & dynamics

Elkarhat Z, Charoute H, Elkhattabi L, Barakat A, Rouba H.
PMID: 32873176
J Biomol Struct Dyn. 2020 Sep 02;1-14. doi: 10.1080/07391102.2020.1813628. Epub 2020 Sep 02.

The SARS-cov-2 RNA dependent RNA polymerase (nsp12) is a crucial viral enzyme that catalyzes the replication of RNA from RNA templates. The fixation of some ligands in the active site may alter the viral life cycle. The aim of...

Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB.

Evidence-based child health : a Cochrane review journal

Sharma SK, Sharma A, Kadhiravan T, Tharyan P.
PMID: 25404581
Evid Based Child Health. 2014 Mar;9(1):169-294. doi: 10.1002/ebch.1962.

BACKGROUND: Preventing active tuberculosis (TB) from developing in people with latent tuberculosis infection (LTBI) is important for global TB control. Isoniazid (INH) for six to nine months has 60% to 90% protective efficacy, but the treatment period is long,...

Recent Developments in Epidemiology, Treatment, and Diagnosis of Tuberculosis.

Current infectious disease reports

Hamilton CD.
PMID: 11095771
Curr Infect Dis Rep. 1999 Apr;1(1):80-88. doi: 10.1007/s11908-999-0014-6.

The resurgence in cases of active tuberculosis in North America in the past decade has prompted increases in funding for tuberculosis treatment, research, and education. As a result, the number of new cases of tuberculosis has declined and cases...

Showing 1 to 12 of 65 entries