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Protective Effect of Aldo-keto Reductase 1B1 Against Neuronal Cell Damage Elicited by 4'-Fluoro-α-pyrrolidinononanophenone.

Neurotoxicity research

Morikawa Y, Miyazono H, Kamase K, Suenami K, Sasajima Y, Sato K, Endo S, Monguchi Y, Takekoshi Y, Ikari A, Matsunaga T.
PMID: 34043181
Neurotox Res. 2021 Aug;39(4):1360-1371. doi: 10.1007/s12640-021-00380-8. Epub 2021 May 27.

Chronic exposure to cathinone derivatives increases the risk of severe health hazards, whereas little is known about the detailed pathogenic mechanisms triggered by the derivatives. We have recently shown that treatment with α-pyrrolidinononanophenone (α-PNP, a highly lipophilic cathinone derivative...

Diabetes-induced auditory complications: are they preventable? a comprehensive review of interventions.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Hajiabolhassan F, Tavanai E.
PMID: 33555440
Eur Arch Otorhinolaryngol. 2021 Oct;278(10):3653-3665. doi: 10.1007/s00405-021-06630-x. Epub 2021 Feb 08.

Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels, which, over time, lead to major chronic complications in various organs of the body. A growing body of research suggests that diabetes could also result in...

Effect of aldose reductase inhibition on heart rate variability in patients with severe or moderate diabetic autonomic neuropathy.

Clinical drug investigation

Didangelos TP, Athyros VG, Karamitsos DT, Papageorgiou AA, Kourtoglou GI, Kontopoulos AG.
PMID: 18370475
Clin Drug Investig. 1998;15(2):111-21. doi: 10.2165/00044011-199815020-00005.

Patients with diabetic autonomic neuropathy (DAN) have an increased cardiovascular mortality rate compared with diabetic patients without DAN. Heart rate variability (HRV) time and frequency domain indices are strong predictors of malignant arrhythmias and sudden cardiac death. This prospective,...

Showing 1 to 3 of 3 entries