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Showing 1 to 12 of 73 entries
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Self-report of memory and affective dysfunction in association with medication use in a sample of individuals with chronic sleep disturbance.

Human psychopharmacology

McAndrews MP, Kayumov L, Phillipson R, Shapiro CM.
PMID: 12404610
Hum Psychopharmacol. 2000 Dec;15(8):583-587. doi: 10.1002/hup.226.

Benzodiazepines produce memory disturbance after acute administration. It is not clear whether chronic use of benzodiazepines is hazardous to memory processes. Epidemiological data indicate that a large proportion (10-30 per cent) of individuals with sleep dysfunction take hypnotic aids...

Eszopiclone: its use in the treatment of insomnia.

Neuropsychiatric disease and treatment

Monti JM, Pandi-Perumal SR.
PMID: 19300573
Neuropsychiatr Dis Treat. 2007 Aug;3(4):441-53.

Eszopiclone is the S-isomer of racemic zopiclone, a cyclopyrrolone with sedative-hypnotic activity that has been available in Europe, Canada, and Latin America since 1987. Eszopiclone acts by binding to the GABA(A) receptor. In contrast to the benzodiazepine (BZD) hypnotics,...

Effects of psychotropic drugs on digit substitution: comparison of the computerized symbol-digit substitution and traditional digit-symbol substitution tests.

Journal of psychopharmacology (Oxford, England)

Mattila MJ, Aranko K, Mattila ME, Paakkari I.
PMID: 22298533
J Psychopharmacol. 1994 Jan;8(2):81-7. doi: 10.1177/026988119400800202.

The digit-symbol substitution test (DSST), performed with paper and pencil or computerized, is widely used to reveal decrements in human attention and cognition. We programmed sets of adjustable tasks (digit-symbol, digit-digit, symbol-digit, symbol-symbol) into a microcomputer and compared the...

Differential illness intrusiveness associated with sleep-promoting medications.

European psychiatry : the journal of the Association of European Psychiatrists

Devins G, Flanigan M, Fleming J, Morehouse R, Moscovitch A, Plamondon J, Reinish L, Shapiro C.
PMID: 19698412
Eur Psychiatry. 1995;10:153s-9s. doi: 10.1016/0924-9338(96)80097-6.

Differences in daytime sleepiness, lifestyle disruptions, and emotional distress were compared across nine groups taking sleep-promoting substances. Groups included individuals taking zopiclone (n = 274), amitriptyline (n = 107), lorazepam (n = 258), oxazepam (n= 141), diphenhydramine HCl (n...

Effects of hypnotics on sleep quality and daytime well-being. Data from a comparative multicentre study in outpatients with insomnia.

European psychiatry : the journal of the Association of European Psychiatrists

Hajak G, Clarenbach P, Fischer W, Haase W, Bandelow B, Adler L, Rüther E.
PMID: 19698415
Eur Psychiatry. 1995;10:173s-9s. doi: 10.1016/0924-9338(96)80100-3.

The effect of treatment (28 days) with zopiclone, triazolam, flunitrazepam and placebo on sleep quality and daytime well-being was proven in a randomised, double-blind, parallel group, multicentre study in private practice. Results of an exploratory statistic of treatment efficacy...

Medications prescribed and occurrence of falls in general medicine inpatients.

The Canadian journal of hospital pharmacy

Cashin RP, Yang M.
PMID: 22479083
Can J Hosp Pharm. 2011 Sep;64(5):321-6. doi: 10.4212/cjhp.v64i5.1066.

BACKGROUND: Although falls are multifactorial, medications are a key risk factor that may be modifiable. Falls were among the most common occurrences entered into a risk identification system at the authors' hospital.OBJECTIVES: To identify whether general medicine inpatients who...

A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients.

Neuropsychiatric disease and treatment

Chen LF, Lin CE, Chou YC, Mao WC, Chen YC, Tzeng NS.
PMID: 23976857
Neuropsychiatr Dis Treat. 2013;9:1159-62. doi: 10.2147/NDT.S48152. Epub 2013 Aug 09.

OBJECTIVE: Complex sleep behaviors (CSBs) are classified as "parasomnias" in the International Classifcation of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients...

Indirect synchronous fluorescence spectroscopy and direct high-performance thin-layer chromatographic methods for enantioseperation of zopiclone and determination of chiral-switching eszopiclone: Evaluation of thermodynamic quantities of chromatographic separation.

Chirality

Moussa BA, Youssef NF, Elkady EF, Mohamed MF.
PMID: 30859633
Chirality. 2019 May;31(5):362-374. doi: 10.1002/chir.23063. Epub 2019 Mar 12.

Economic and enantioselective synchronous fluorescence spectroscopy and high-performance thin-layer chromatography methods have been developed and validated as per ICH guidelines for the separation of zopiclone enantiomers using L-(+)-tartaric acid as a chiral selector, followed by determination of the chiral-switching...

Sol-gel technique for the preparation of β-cyclodextrin gold nanoparticles as chiral stationary phase in open-tubular capillary electrochromatography.

Journal of separation science

Jiang Z, Qu J, Tian X, Huo X, Zhang J, Guo X, Fang L.
PMID: 30919564
J Sep Sci. 2019 May;42(10):1948-1954. doi: 10.1002/jssc.201900071. Epub 2019 Apr 16.

A novel open-tubular capillary electrochromatography column coated with β-cyclodextrin was prepared using the sol-gel technique. In the sol-gel approach, owing to the three-dimensional network of sol-gel and the strong chemical bond between the stationary phase and the surface of...

Simulated driving performance in healthy adults after night-time administration of 20 mg tasimelteon.

Journal of sleep research

Torres R, Fisher M, Birznieks G, Polymeropoulos C, Kay GG, Xiao C, Polymeropoulos MH.
PMID: 34152055
J Sleep Res. 2021 Jun 21;e13430. doi: 10.1111/jsr.13430. Epub 2021 Jun 21.

An impairment in next day driving performance has been reported for almost every drug currently United States Food and Drug Administration (FDA) approved for improvement of sleep in chronic and transient insomnia. Tasimelteon, a melatonin receptor agonist, demonstrated significant...

Use of potentially driver-impairing drugs among older drivers.

BMC geriatrics

Zitoun S, Baudouin E, Corruble E, Vidal JS, Becquemont L, Duron E.
PMID: 34979970
BMC Geriatr. 2022 Jan 03;22(1):4. doi: 10.1186/s12877-021-02726-5.

BACKGROUND: Road safety is a major issue among seniors. Potentially Driver-Impairing (PDI) drugs are known to increase the risk of car accident. The aim of this cross-sectional study was to describe PDI-drug consumption among older drivers and determine associated...

The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer's disease: a randomized, triple-blind, placebo-controlled trial.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Louzada LL, Machado FV, Quintas JL, Ribeiro GA, Silva MV, Mendonça-Silva DL, Gonçalves BSB, Nóbrega OT, Camargos EF.
PMID: 34635802
Neuropsychopharmacology. 2022 Jan;47(2):570-579. doi: 10.1038/s41386-021-01191-3. Epub 2021 Oct 11.

No prior studies have evaluated the efficacy and safety of zolpidem and zopiclone to treat insomnia of demented patients. This randomized, triple-blind, placebo-controlled clinical trial used these drugs to treat patients with probable, late onset Alzheimer's dementia (AD) (DSM...

Showing 1 to 12 of 73 entries