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Showing 1 to 4 of 4 entries
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[Association between microsatellite instability and clinico-pathological characteristics in sporadic colon cancer].

Medicina clinica

Guerrero D, Balen E, Martínez-Peñuela JM, García-Foncillas J, Larrinaga B, Caballero MC, Herrera J, Lera JM.
PMID: 15826579
Med Clin (Barc). 2005 Apr 02;124(12):441-6. doi: 10.1157/13073216.

BACKGROUND AND OBJECTIVE: Currently, colon cancer is a leading cause of cancer death world-wide. It progresses according to three molecular pathways, named suppressor, mutador and methylator. Microsatellite instability is a hallmark of the lack of reparation, of DNA mismatches...

The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy.

Cancer discovery

Xiao Y, Freeman GJ.
PMID: 25583798
Cancer Discov. 2015 Jan;5(1):16-8. doi: 10.1158/2159-8290.CD-14-1397.

The microsatellite instable (MSI) subset of colorectal cancer exhibits an active Th1/CTL immune microenvironment, probably due to recognition of a high number of tumor neoantigens. However, the high expression of checkpoint molecules PD-1, PD-L1, CTLA-4, LAG-3, and IDO in...

[Molecular pathology of colon cancer].

Polish journal of pathology : official journal of the Polish Society of Pathologists

Bosman FT, Yan P.
PMID: 26165028
Pol J Pathol. 2014 Dec;65(4):S1-11.

No abstract available.

Familial colorectal cancer: a genetics treasure trove for medical discovery.

JAMA

Pasche B.
PMID: 18523226
JAMA. 2008 Jun 04;299(21):2564-5. doi: 10.1001/jama.299.21.2564.

No abstract available.

Showing 1 to 4 of 4 entries