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Showing 1 to 12 of 15 entries
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[Genetic factors and colorectal cancers development: therapeutic impact].

Medecine sciences : M/S

Olschwang S, Viret F, Monges G, Seitz J, Sevenet N, Tiret E, Milano G, Birnbaum D, Bertucci F.
PMID: 16705943
Med Sci (Paris). 2006 Jan;22:45-9. doi: 10.1051/medsci/2006221s45.

Colorectal tumorigenesis is associated with the progressive increase of epithelium dysplasia and wall invasion. These criteria are evaluated through histological staging, that enables a reliable estimation of patient prognosis, and is the best tool for therapeutic decision. Adjuvant chemotherapy...

[Chemotherapy of colorectal carcinoma].

Srpski arhiv za celokupno lekarstvo

Jelić S, Nikolić-Tomasević Z, Popov I, Radosavljević D.
PMID: 9921027
Srp Arh Celok Lek. 1998 Nov-Dec;126(11):506-11.

The benefit of adjuvant therapy in colorectal cancer (CRC) has been provided in clinical studies that have demonstrated reduction of up to 30% in a 5-year overall mortality in patients (pts.) with TNM stage III (Dukes' stage C) carcinoma....

Issues remain for treating colorectal cancer.

Journal of the National Cancer Institute

Reynolds T.
PMID: 7707431
J Natl Cancer Inst. 1995 Apr 05;87(7):480. doi: 10.1093/jnci/87.7.480.

No abstract available.

The role of PDGFRA as a therapeutic target in young colorectal cancer patients.

Journal of translational medicine

Kim TW, Hong HK, Lee C, Kim S, Lee WY, Yun SH, Kim HC, Huh JW, Park YA, Joung JG, Park WY, Cho YB.
PMID: 34702313
J Transl Med. 2021 Oct 26;19(1):446. doi: 10.1186/s12967-021-03088-7.

BACKGROUND: Young patients with colorectal cancer (CRC) exhibit poor prognoses compared to older patients due to the difficulty in early diagnosis and treatment. However, the underlying molecular characteristics are still unclear.METHODS: We conducted a comprehensive analysis of 49 CRC...

The emergence of targetable pathways in colorectal cancer.

Clinical advances in hematology & oncology : H&O

Yu IS, Kopetz S.
PMID: 34928933
Clin Adv Hematol Oncol. 2021 Dec;19(12):774-783.

Colorectal cancer continues to be one of the leading causes of cancer-related morbidity and mortality globally. Despite an overall decreasing incidence of the disease, early-onset colorectal cancer is a growing concern. Fluoropyrimidine-based doublet chemotherapy has remained the backbone of...

[Selection of a molecule-target agent--present and prospect].

Nihon rinsho. Japanese journal of clinical medicine

Takahashi N, Hamaguchi T.
PMID: 22214008
Nihon Rinsho. 2011 Apr;69:482-6.

No abstract available.

[Ⅲ.Japanese Society for Cancer of the Colon and Rectum(JSCCR)Guidelines 2019 for the Treatment of Colorectal Cancer:Systemic Therapy].

Gan to kagaku ryoho. Cancer & chemotherapy

Taniguchi H.
PMID: 31748479
Gan To Kagaku Ryoho. 2019 Nov;46(11):1709-1713.

No abstract available.

Current status and perspectives of immune checkpoint inhibitors for colorectal cancer.

Japanese journal of clinical oncology

Hirano H, Takashima A, Hamaguchi T, Shida D, Kanemitsu Y.
PMID: 33205813
Jpn J Clin Oncol. 2021 Jan 01;51(1):10-19. doi: 10.1093/jjco/hyaa200.

Immunotherapy, especially immune checkpoint inhibitors, has revolutionized the standard-of-care of multiple types of tumors. For colorectal cancer, the clinical development of immune checkpoint inhibitors is mainly separated according to the status of microsatellite instability or mismatch repair in a...

Letter to the Editor from Colle .

Journal for immunotherapy of cancer

Colle R, Andre T, Menu Y.
PMID: 34162716
J Immunother Cancer. 2021 Jun;9(6). doi: 10.1136/jitc-2021-002997.

In their article, Fucà

Outcomes and toxicities of immune checkpoint inhibitors in colorectal cancer: a real-world retrospective analysis.

Cancer communications (London, England)

Zhou C, Jiang T, Li R, Yuan Y, Xie W, Huang X, Wang Q, Chang H, Chen G, Li Y, Zeng Z, Xiao W, Gao Y.
PMID: 34327863
Cancer Commun (Lond). 2021 Sep;41(9):921-924. doi: 10.1002/cac2.12199. Epub 2021 Jul 30.

No abstract available.

The Role of Maintenance Therapy in Metastatic Colorectal Cancer.

JAMA oncology

Wang ZX, Liang F, Xu RH.
PMID: 32297912
JAMA Oncol. 2020 Jun 01;6(6):937. doi: 10.1001/jamaoncol.2020.0580.

No abstract available.

Colorectal Cancer Subtypes - The Current Portrait.

Advances in experimental medicine and biology

Jordan P.
PMID: 30623362
Adv Exp Med Biol. 2018;1110:1-6. doi: 10.1007/978-3-030-02771-1_1.

Colorectal cancer (CRC) is one prominent example for how chemotherapy has been changing by moving from the use of general cytotoxic agents to more tumour-specific drugs. For example, antibody-based drugs neutralize a growth factor receptor protein on the surface...

Showing 1 to 12 of 15 entries