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Showing 1 to 7 of 7 entries
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Cytokines and Chemokines in SARS-CoV-2 Infections-Therapeutic Strategies Targeting Cytokine Storm.

Biomolecules

Pum A, Ennemoser M, Adage T, Kungl AJ.
PMID: 33445810
Biomolecules. 2021 Jan 12;11(1). doi: 10.3390/biom11010091.

The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic, frequently leads to severe respiratory distress syndrome and pneumonia with fatal consequences. Although several factors of this...

Analysis of inflammatory signals in Japanese children with Crohn's disease.

Pediatrics international : official journal of the Japan Pediatric Society

Fujitake Y, Ohtsuka Y, Ikuse T, Ohtani K, Aoyagi Y, Fujii T, Kudo T, Ishii M, Shimizu T.
PMID: 23773416
Pediatr Int. 2013 Dec;55(6):753-6. doi: 10.1111/ped.12159. Epub 2013 Aug 21.

BACKGROUND: Although it is recognized that the Th1 and Th17 cytokines are directly involved in the pathogenesis of Crohn's disease (CD), the precise cause of pediatric CD in the Japanese population has not been well established. In the present...

Complexity of immune responses in COVID-19.

Seminars in immunology

Mather MW, Jardine L, Talks B, Gardner L, Haniffa M.
PMID: 34865933
Semin Immunol. 2021 Jun;55:101545. doi: 10.1016/j.smim.2021.101545. Epub 2021 Nov 27.

The global COVID-19 pandemic has caused substantial morbidity and mortality to humanity. Remarkable progress has been made in understanding both the innate and adaptive mechanisms involved in the host response to the causative SARS-CoV-2 virus, but much remains to...

Hazards of the Cytokine Storm and Cytokine-Targeted Therapy in Patients With COVID-19: Review.

Journal of medical Internet research

Quirch M, Lee J, Rehman S.
PMID: 32707537
J Med Internet Res. 2020 Aug 13;22(8):e20193. doi: 10.2196/20193.

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged medicine and health care on a global scale. Its impact and frightening mortality rate are in large part attributable to the fact that there is a lack of available...

Review: cytokines and the pathogenesis of multiple sclerosis.

Journal of neuroscience research

Navikas V, Link H.
PMID: 8872892
J Neurosci Res. 1996 Aug 15;45(4):322-33. doi: 10.1002/(SICI)1097-4547(19960815)45:4<322::AID-JNR1>3.0.CO;2-B.

Perivascular accumulation of mononuclear cells (MNCs) in the central nervous system (CNS) and high levels of myelin autoantigen-reactive T cells in blood and further enriched in cerebrospinal fluid (CSF) are characteristic for multiple sclerosis (MS) and suggest a role...

[The role of cytokines in the development and clinical course of cardiac insufficiency].

Klinicheskaia meditsina

Kravchenko AIa, Cherniaeva IuM.
PMID: 25696944
Klin Med (Mosk). 2013;91(10):11-6.

The review is focused on the main premises of the theory of progressive cardiac insufficiency based on the notion of immune activation and systemic inflammation as markers of adverse prognosis and high risk of cardiovascular complications. The relationship between...

Th17 cells associated cytokines and cancer.

European review for medical and pharmacological sciences

Feng S, Chen XM, Wang JF, Xu XQ.
PMID: 27775796
Eur Rev Med Pharmacol Sci. 2016 Oct;20(19):4032-4040.

Cancer is one of the most common malignant tumors, which is a serious threat to human life. However, the etiology of cancer is not entirely clear. Under the action of tumorigenic factors, tissue cells lose normal regulation, resulting in...

Showing 1 to 7 of 7 entries