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Showing 1 to 12 of 83 entries
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Gene × environment interactions in type 2 diabetes.

Current diabetes reports

Franks PW.
PMID: 21887612
Curr Diab Rep. 2011 Dec;11(6):552-61. doi: 10.1007/s11892-011-0224-9.

People vary genetically in their susceptibility to the effects of environmental risk factors for many diseases. Genetic variation also underlies the extent to which people respond appropriately to clinical therapies. Defining the basis to the interactions between the genome...

Path to Personalized Medicine for Type 2 Diabetes Mellitus: Reality and Hope.

Acta medica Iranica

Aghaei Meybodi HR, Hasanzad M, Larijani B.
PMID: 28282717
Acta Med Iran. 2017 Mar;55(3):166-174.

Type 2 diabetes mellitus (T2DM) is recognized as a public health problem and increasingly prevalent illness. Key elements of the guideline for diabetes care are based on evidence-based medicine approach and apply for population, not individuals. However, individualized care...

Diabetes: DNA methylation affects T2DM risk.

Nature reviews. Endocrinology

Greenhill C.
PMID: 26149612
Nat Rev Endocrinol. 2015 Sep;11(9):505. doi: 10.1038/nrendo.2015.110. Epub 2015 Jul 07.

No abstract available.

Advances in risk prediction of type 2 diabetes: integrating genetic scores with Framingham risk models.

Diabetes

Keating BJ.
PMID: 25908872
Diabetes. 2015 May;64(5):1495-7. doi: 10.2337/db15-0033.

No abstract available.

[Is it our genes or our lifestyle that determines the risk for diabetes? Results from diabetes cohort study have no relevance in clinical practice].

Deutsche medizinische Wochenschrift (1946)

Nawroth PP.
PMID: 24983191
Dtsch Med Wochenschr. 2014 Jul;139(28):1452. doi: 10.1055/s-0033-1353911. Epub 2014 Jul 01.

No abstract available.

[Gene mutations in diabetes mellitus].

Nihon rinsho. Japanese journal of clinical medicine

Kasuga M.
PMID: 9392132
Nihon Rinsho. 1997 Oct;55:365-9.

No abstract available.

[Non-insulin-dependent diabetes mellitus--strategies and problems in genetic research].

Vnitrni lekarstvi

Bendlová B, Mazura I, Vcelák J, Perusicová J.
PMID: 9012119
Vnitr Lek. 1996 Nov;42(11):761-6.

Non-insulin dependent diabetes mellitus (NIDDM) is at present one of the most serious and widespread diseases with a mass incidence and its treatment is very costly. In the genesis and development of the disease genetic factors participate along with...

More diabetes genes.

Diabetes forecast

Ruder K.
PMID: 17707995
Diabetes Forecast. 2007 Jul;60(8):34.

No abstract available.

[Mutations of transcription factors in relation to the metabolic syndrome].

Nihon rinsho. Japanese journal of clinical medicine

Teraucho Y.
PMID: 17458240
Nihon Rinsho. 2006 Dec 28;64:324-9.

No abstract available.

Preventing type 2 diabetes: genes or lifestyle?.

Primary care diabetes

Weber MB, Narayan KM.
PMID: 18684424
Prim Care Diabetes. 2008 Jun;2(2):65-6. doi: 10.1016/j.pcd.2008.03.005. Epub 2008 May 07.

Type 2 diabetes is a complex, multi-factorial condition, caused by environment factors and an inheritance pattern that is polygenic. Preventing diabetes is a major clinical, research and public health priority. Lifestyle intervention studies, programs that promote changes in diet,...

Genetics of type 2 diabetes: the GWAS era and future perspectives [Review].

Endocrine journal

Imamura M, Maeda S.
PMID: 21778616
Endocr J. 2011;58(9):723-39. doi: 10.1507/endocrj.ej11-0113. Epub 2011 Jul 20.

Genome-wide association studies (GWAS) have facilitated a substantial and rapid rise in the number of confirmed genetic susceptibility variants for type 2 diabetes (T2D). Approximately 40 variants have been identified so far, many of which were discovered through GWAS....

[Diabetes susceptibility genes].

Nihon rinsho. Japanese journal of clinical medicine

Kasuga M.
PMID: 19507498
Nihon Rinsho. 2009 Jun;67(6):1090-4.

Type 2 diabetes mellitus is a complex polygenic disorder in which common genetics variants interact with environmental factors. Genome-wide association study(GWAS) revealed more than 10 diabetes susceptibility loci for type 2 diabetes mellitus including SNPs in KCNQ1, which was...

Showing 1 to 12 of 83 entries