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Showing 1 to 10 of 10 entries
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Dried blood spots: analysis and applications.

Analytical chemistry

Demirev PA.
PMID: 23171435
Anal Chem. 2013 Jan 15;85(2):779-89. doi: 10.1021/ac303205m. Epub 2012 Dec 04.

No abstract available.

Bioanalysis zone: DBS survey results.

Bioanalysis

Denniff P, Holliman C, Svensson L, Weng N, Patel S.
PMID: 24471950
Bioanalysis. 2014 Feb;6(3):287-91. doi: 10.4155/bio.13.327.

Bioanalysis Zone carried out a survey to evaluate the use of and attitudes to DBS analysis among our readership in the bioanalytical community. DBS analysis has generated a huge amount of interest in recent years. We wanted to take...

EBF and dried blood spots: from recommendations to potential resolution.

Bioanalysis

Timmerman P, White S, Globig S, Lüdtke S, Brunet L, Smith C, Smeraglia J.
PMID: 21877884
Bioanalysis. 2011 Aug;3(16):1787-9. doi: 10.4155/bio.11.191.

No abstract available.

An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.

The AAPS journal

Kothare PA, Bateman KP, Dockendorf M, Stone J, Xu Y, Woolf E, Shipley LA.
PMID: 26857396
AAPS J. 2016 Mar;18(2):519-27. doi: 10.1208/s12248-015-9860-3. Epub 2016 Feb 08.

Dried blood spot (DBS) sample collection has gained increased interest across the pharmaceutical industry as a potential alternative to plasma for pharmacokinetic (PK) evaluations. However, regulatory guidelines and examples of late-stage clinical trial applications in the literature are lacking....

Bridging the Polar and Hydrophobic Metabolome in Single-Run Untargeted Liquid Chromatography-Mass Spectrometry Dried Blood Spot Metabolomics for Clinical Purposes.

Journal of proteome research

Skogvold HB, Sandås EM, Østeby A, Løkken C, Rootwelt H, Rønning PO, Wilson SR, Elgstøen KBP.
PMID: 34296888
J Proteome Res. 2021 Aug 06;20(8):4010-4021. doi: 10.1021/acs.jproteome.1c00326. Epub 2021 Jul 23.

Dried blood spot (DBS) metabolite analysis is a central tool for the clinic, e.g., newborn screening. Instead of applying multiple analytical methods, a single liquid chromatography-mass spectrometry (LC-MS) method was developed for metabolites spanning from highly polar glucose to...

Use of dried blood spots to study excipient kinetics in neonates.

Bioanalysis

Yakkundi S, McElnay J, Millership J, Mulla H, Pandya H, Shah U, Nunn T, Rieutord A, Storme T, Vaconsin P, Metsvaht T, Varendi H, Nellis G, Lutsar I, Turner M.
PMID: 22185265
Bioanalysis. 2011 Dec;3(24):2691-3. doi: 10.4155/bio.11.277.

No abstract available.

Newborn screening by sequence and the road ahead.

Clinical chemistry

Sondheimer N.
PMID: 23529705
Clin Chem. 2013 Jul;59(7):1011-3. doi: 10.1373/clinchem.2013.205864. Epub 2013 Mar 25.

No abstract available.

Using dried blood spot samples from a trio for linked-read whole-exome sequencing.

European journal of human genetics : EJHG

Mortensen Ó, Lydersen LN, Apol KD, Andorsdóttir G, Steig BÁ, Gregersen NO.
PMID: 30765883
Eur J Hum Genet. 2019 Jun;27(6):980-988. doi: 10.1038/s41431-019-0343-3. Epub 2019 Feb 14.

Long-term collection of dried blood spot (DBS) samples through newborn screening may have retrospective and prospective advantages, especially in combination with advanced analytical techniques. This work concerns whether linked-reads may overcome some of the limitations of short-read sequencing of...

Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.

Clinical chemistry

Kahraman M, Laufer T, Backes C, Schrörs H, Fehlmann T, Ludwig N, Kohlhaas J, Meese E, Wehler T, Bals R, Keller A.
PMID: 28679647
Clin Chem. 2017 Sep;63(9):1476-1488. doi: 10.1373/clinchem.2017.271619. Epub 2017 Jul 05.

BACKGROUND: Different work flows have been proposed to use miRNAs as blood-borne biomarkers. In particular, the method used for collecting blood from patients can considerably influence the diagnostic results.METHODS: We explored whether dried blood spots (DBSs) facilitate stable miRNA...

Stabilized dried blood spot collection.

Analytical biochemistry

McMorran D, Chung DC, Toth M, Liew OW, Muradoglu M, Ng TW.
PMID: 27156813
Anal Biochem. 2016 Aug 01;506:28-30. doi: 10.1016/j.ab.2016.04.015. Epub 2016 May 05.

During the collection phase of the dried blood spot method, practitioners need to ensure that there is no smearing of the blood sample on the filter paper or else readings from it will be invalid. This can be difficult...

Showing 1 to 10 of 10 entries