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Structure-based drug design.

Current opinion in structural biology

Colman PM.
PMID: 7712290
Curr Opin Struct Biol. 1994 Dec;4(6):868-74. doi: 10.1016/0959-440x(94)90268-2.

There are now many successful examples of the design of new ligands based on knowledge of target protein structures. In most cases those ligands are unsuitable as drugs because of problems of toxicity, stability or bioavailability. The past twelve...

Showing 1 to 1 of 1 entries