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The bright future of single-molecule fluorescence imaging.

Current opinion in chemical biology

Juette MF, Terry DS, Wasserman MR, Zhou Z, Altman RB, Zheng Q, Blanchard SC.
PMID: 24956235
Curr Opin Chem Biol. 2014 Jun;20:103-11. doi: 10.1016/j.cbpa.2014.05.010. Epub 2014 Jun 21.

Single-molecule Förster resonance energy transfer (smFRET) is an essential and maturing tool to probe biomolecular interactions and conformational dynamics in vitro and, increasingly, in living cells. Multi-color smFRET enables the correlation of multiple such events and the precise dissection...

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