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Showing 1 to 12 of 148 entries
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Social network Analysis-based classifier (SNAc): A case study on time course gene expression data.

Computer methods and programs in biomedicine

Üçer S, Koçak Y, Ozyer T, Alhajj R.
PMID: 28859830
Comput Methods Programs Biomed. 2017 Oct;150:73-84. doi: 10.1016/j.cmpb.2017.06.015. Epub 2017 Jul 24.

BACKGROUND AND OBJECTIVES: Social Network Analysis is an attractive approach to model and analyze complex networks. In recent years, several bioinformatics related networks have been modeled and analyzed thoroughly using social network analysis. The objective of this study is...

A composite framework for the statistical analysis of epidemiological DNA methylation data with the Infinium Human Methylation 450K BeadChip.

IEEE journal of biomedical and health informatics

Valavanis I, Sifakis EG, Georgiadis P, Kyrtopoulos S, Chatziioannou AA.
PMID: 24808224
IEEE J Biomed Health Inform. 2014 May;18(3):817-23. doi: 10.1109/JBHI.2014.2298351.

High-throughput DNA methylation profiling exploits microarray technologies thus providing a wealth of data, which however solicits rigorous, generic, and analytical pipelines for an efficient systems level analysis and interpretation. In this study, we utilize the Illumina's Infinium Human Methylation...

Identification of sample annotation errors in gene expression datasets.

Archives of toxicology

Lohr M, Hellwig B, Edlund K, Mattsson JS, Botling J, Schmidt M, Hengstler JG, Micke P, Rahnenführer J.
PMID: 26608184
Arch Toxicol. 2015 Dec;89(12):2265-72. doi: 10.1007/s00204-015-1632-4. Epub 2015 Nov 25.

The comprehensive transcriptomic analysis of clinically annotated human tissue has found widespread use in oncology, cell biology, immunology, and toxicology. In cancer research, microarray-based gene expression profiling has successfully been applied to subclassify disease entities, predict therapy response, and...

FunRich: An open access standalone functional enrichment and interaction network analysis tool.

Proteomics

Pathan M, Keerthikumar S, Ang CS, Gangoda L, Quek CY, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim A, Bacic A, Hill AF, Stroud DA, Ryan MT, Agbinya JI, Mariadason JM, Burgess AW, Mathivanan S.
PMID: 25921073
Proteomics. 2015 Aug;15(15):2597-601. doi: 10.1002/pmic.201400515. Epub 2015 Jun 17.

As high-throughput techniques including proteomics become more accessible to individual laboratories, there is an urgent need for a user-friendly bioinformatics analysis system. Here, we describe FunRich, an open access, standalone functional enrichment and network analysis tool. FunRich is designed...

A high-throughput microRNA expression profiling system.

Methods in molecular biology (Clifton, N.J.)

Guo Y, Mastriano S, Lu J.
PMID: 25030917
Methods Mol Biol. 2014;1176:33-44. doi: 10.1007/978-1-4939-0992-6_4.

As small noncoding RNAs, microRNAs (miRNAs) regulate diverse biological functions, including physiological and pathological processes. The expression and deregulation of miRNA levels contain rich information with diagnostic and prognostic relevance and can reflect pharmacological responses. The increasing interest in...

Differentiating disease subtypes by using pathway patterns constructed from gene expressions and protein networks.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Hung FH, Chiu HW.
PMID: 26737786
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:6519-22. doi: 10.1109/EMBC.2015.7319886.

Gene expression profiles differ in different diseases. Even if diseases are at the same stage, such diseases exhibit different gene expressions, not to mention the different subtypes at a single lesion site. Distinguishing different disease subtypes at a single...

Jets: a modification to speed flexible oligonucleotide array construction.

The pharmacogenomics journal

Yoder B, Sell SM.
PMID: 11908749
Pharmacogenomics J. 2001;1(3):163-5. doi: 10.1038/sj.tpj.6500032.

No abstract available.

Statistical methods for identifying differentially expressed genes in DNA microarrays.

Methods in molecular biology (Clifton, N.J.)

Storey JD, Tibshirani R.
PMID: 12710672
Methods Mol Biol. 2003;224:149-57. doi: 10.1385/1-59259-364-X:149.

No abstract available.

Gene expression analysis on medium-density oligonucleotide arrays.

Methods in molecular biology (Clifton, N.J.)

Sinibaldi R, O'Connell C, Seidel C, Rodriguez H.
PMID: 11357684
Methods Mol Biol. 2001;170:211-22. doi: 10.1385/1-59259-234-1:211.

No abstract available.

Use of bioinformatics in arrays.

Methods in molecular biology (Clifton, N.J.)

Kalocsai P, Shams S.
PMID: 11357685
Methods Mol Biol. 2001;170:223-36. doi: 10.1385/1-59259-234-1:223.

No abstract available.

Critical assessment of microarray data analysis: the 2001 challenge.

Bioinformatics (Oxford, England)

Johnson KF, Lin SM.
PMID: 11590109
Bioinformatics. 2001 Sep;17(9):857-8. doi: 10.1093/bioinformatics/17.9.857.

UNLABELLED: We initiated the Critical Assessment of Microarray Data Analysis (CAMDA) conference to stimulate and evaluate the development of advanced data analysis techniques for microarrays. A standard data set has been released for this data analysis challenge. The goal...

PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways.

Nucleic acids research

Mlecnik B, Scheideler M, Hackl H, Hartler J, Sanchez-Cabo F, Trajanoski Z.
PMID: 15980551
Nucleic Acids Res. 2005 Jul 01;33:W633-7. doi: 10.1093/nar/gki391.

While generation of high-throughput expression data is becoming routine, the fast, easy, and systematic presentation and analysis of these data in a biological context is still an obstacle. To address this need, we have developed PathwayExplorer, which maps expression...

Showing 1 to 12 of 148 entries