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Showing 1 to 12 of 92 entries
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Experimental investigation and computational modeling of hydrodynamics in bifurcating microchannels.

Biomedical microdevices

Janakiraman V, Sastry S, Kadambi JR, Baskaran H.
PMID: 18175219
Biomed Microdevices. 2008 Jun;10(3):355-65. doi: 10.1007/s10544-007-9143-6.

Methods involving microfluidics have been used in several chemical, biological and medical applications. In particular, a network of bifurcating microchannels can be used to distribute flow in a large space. In this work, we carried out experiments to determine...

Electrospray ionization from a gap with adjustable width.

Rapid communications in mass spectrometry : RCM

Ek P, Sjödahl J, Roeraade J.
PMID: 17016803
Rapid Commun Mass Spectrom. 2006;20(21):3176-82. doi: 10.1002/rcm.2710.

In this paper, we present a new concept for electrospray ionization mass spectrometry, where the sample is applied in a gap which is formed between the edges of two triangular-shaped tips. The size of the spray orifice can be...

Effect of nonuniform surface potential on electroosmotic flow at large applied electric field strength.

Biomedical microdevices

Chen L, Conlisk AT.
PMID: 18850273
Biomed Microdevices. 2009 Feb;11(1):251-8. doi: 10.1007/s10544-008-9231-2.

Electroosmotic flow in nanochannels with non-uniform wall potential is investigated. While several researchers have presented results for the case of periodic potential and sudden change in potential, most of the previous work in this area is based on the...

Numerical studies of electrokinetic control of DNA concentration in a closed-end microchannel.

Electrophoresis

Daghighi Y, Li D.
PMID: 20191548
Electrophoresis. 2010 Mar;31(5):868-78. doi: 10.1002/elps.200900447.

A major challenge in lab-on-a-chip devices is how to concentrate sample molecules from a dilute solution, which is critical to the effectiveness and the detection limit of on-chip bio-chemical reactions. A numerical study of sample concentration control by electrokinetic...

Digital microfluidic operations on micro-electrode dot array architecture.

IET nanobiotechnology

Wang G, Teng D, Fan SK.
PMID: 22149873
IET Nanobiotechnol. 2011 Dec;5(4):152-60. doi: 10.1049/iet-nbt.2011.0018.

As digital microfluidics-based biochips find more applications, their complexity is expected to increase significantly owing to the trend of multiple and concurrent assays on the chip. There is a pressing need to deliver a top-down design methodology that the...

Fusion and sorting of two parallel trains of droplets using a railroad-like channel network and guiding tracks.

Lab on a chip

Xu L, Lee H, Panchapakesan R, Oh KW.
PMID: 22814673
Lab Chip. 2012 Oct 21;12(20):3936-42. doi: 10.1039/c2lc40456g.

We propose a robust droplet fusion and sorting method for two parallel trains of droplets that is relatively insensitive to frequency and phase mismatch. Conventional methods of droplet fusion require an extremely precise control of aqueous/oil flows for perfect...

Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers.

Small (Weinheim an der Bergstrasse, Germany)

Kim SJ, Lai D, Park JY, Yokokawa R, Takayama S.
PMID: 22761019
Small. 2012 Oct 08;8(19):2925-34. doi: 10.1002/smll.201200456. Epub 2012 Jul 03.

This paper gives an overview of elastomeric valve- and droplet-based microfluidic systems designed to minimize the need of external pressure to control fluid flow. This Concept article introduces the working principle of representative components in these devices along with...

Measuring the growth rate of cells, one at a time.

Nature methods

Charvin G.
PMID: 20431549
Nat Methods. 2010 May;7(5):363. doi: 10.1038/nmeth0510-363.

No abstract available.

Integrated capture, transport, and magneto-mechanical resonant sensing of superparamagnetic microbeads using magnetic domain walls.

Lab on a chip

Rapoport E, Montana D, Beach GS.
PMID: 22955796
Lab Chip. 2012 Nov 07;12(21):4433-40. doi: 10.1039/c2lc40715a.

An integrated platform for the capture, transport, and detection of individual superparamagnetic microbeads is described for lab-on-a-chip biomedical applications. Magnetic domain walls in magnetic tracks have previously been shown to be capable of capturing and transporting individual beads through...

Numerical and experimental characterization of a novel modular passive micromixer.

Biomedical microdevices

Pennella F, Rossi M, Ripandelli S, Rasponi M, Mastrangelo F, Deriu MA, Ridolfi L, Kähler CJ, Morbiducci U.
PMID: 22711456
Biomed Microdevices. 2012 Oct;14(5):849-62. doi: 10.1007/s10544-012-9665-4.

This paper reports a new low-cost passive microfluidic mixer design, based on a replication of identical mixing units composed of microchannels with variable curvature (clothoid) geometry. The micromixer presents a compact and modular architecture that can be easily fabricated...

Programmed trapping of individual bacteria using micrometre-size sieves.

Lab on a chip

Kim MC, Isenberg BC, Sutin J, Meller A, Wong JY, Klapperich CM.
PMID: 21293825
Lab Chip. 2011 Mar 21;11(6):1089-95. doi: 10.1039/c0lc00362j. Epub 2011 Feb 04.

Monitoring the real-time behavior of spatial arrays of single living bacteria cells is only achieved with much experimental difficulty due to the small size and mobility of the cells. To address this problem, we have designed and constructed a...

Droplet microfluidics--a tool for single-cell analysis.

Angewandte Chemie (International ed. in English)

Joensson HN, Andersson Svahn H.
PMID: 23180509
Angew Chem Int Ed Engl. 2012 Dec 03;51(49):12176-92. doi: 10.1002/anie.201200460. Epub 2012 Nov 23.

Droplet microfluidics allows the isolation of single cells and reagents in monodisperse picoliter liquid capsules and manipulations at a throughput of thousands of droplets per second. These qualities allow many of the challenges in single-cell analysis to be overcome....

Showing 1 to 12 of 92 entries