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Showing 1 to 12 of 83 entries
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Droplet Size-Aware and Error-Correcting Sample Preparation Using Micro-Electrode-Dot-Array Digital Microfluidic Biochips.

IEEE transactions on biomedical circuits and systems

Li Z, Lai KY, Chakrabarty K, Ho TY, Lee CY.
PMID: 28976321
IEEE Trans Biomed Circuits Syst. 2017 Dec;11(6):1380-1391. doi: 10.1109/TBCAS.2017.2742548. Epub 2017 Sep 29.

Sample preparation in digital microfluidics refers to the generation of droplets with target concentrations for on-chip biochemical applications. In recent years, digital microfluidic biochips (DMFBs) have been adopted as a platform for sample preparation. However, there remain two major...

A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device.

Journal of laboratory automation

Li Y, Li H, Baker RJ.
PMID: 25609255
J Lab Autom. 2015 Dec;20(6):663-9. doi: 10.1177/2211068214566940. Epub 2015 Jan 21.

A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and...

Experimental investigation and computational modeling of hydrodynamics in bifurcating microchannels.

Biomedical microdevices

Janakiraman V, Sastry S, Kadambi JR, Baskaran H.
PMID: 18175219
Biomed Microdevices. 2008 Jun;10(3):355-65. doi: 10.1007/s10544-007-9143-6.

Methods involving microfluidics have been used in several chemical, biological and medical applications. In particular, a network of bifurcating microchannels can be used to distribute flow in a large space. In this work, we carried out experiments to determine...

Three-dimensional multihelical microfluidic mixers for rapid mixing of liquids.

Langmuir : the ACS journal of surfaces and colloids

Verma MK, Ganneboyina SR, R VR, Ghatak A.
PMID: 18197716
Langmuir. 2008 Mar 04;24(5):2248-51. doi: 10.1021/la702895w. Epub 2008 Jan 16.

Rapid mixing of liquids is important for most microfluidic applications. However, mixing is slow in conventional micromixers, because, in the absence of turbulence, mixing here occurs by molecular diffusion. Recent experiments show that mixing can be enhanced by generating...

Numerical and experimental characterization of a novel modular passive micromixer.

Biomedical microdevices

Pennella F, Rossi M, Ripandelli S, Rasponi M, Mastrangelo F, Deriu MA, Ridolfi L, Kähler CJ, Morbiducci U.
PMID: 22711456
Biomed Microdevices. 2012 Oct;14(5):849-62. doi: 10.1007/s10544-012-9665-4.

This paper reports a new low-cost passive microfluidic mixer design, based on a replication of identical mixing units composed of microchannels with variable curvature (clothoid) geometry. The micromixer presents a compact and modular architecture that can be easily fabricated...

Droplet microfluidics--a tool for single-cell analysis.

Angewandte Chemie (International ed. in English)

Joensson HN, Andersson Svahn H.
PMID: 23180509
Angew Chem Int Ed Engl. 2012 Dec 03;51(49):12176-92. doi: 10.1002/anie.201200460. Epub 2012 Nov 23.

Droplet microfluidics allows the isolation of single cells and reagents in monodisperse picoliter liquid capsules and manipulations at a throughput of thousands of droplets per second. These qualities allow many of the challenges in single-cell analysis to be overcome....

Advances in microfluidics for environmental analysis.

The Analyst

Jokerst JC, Emory JM, Henry CS.
PMID: 22005445
Analyst. 2012 Jan 07;137(1):24-34. doi: 10.1039/c1an15368d. Epub 2011 Oct 18.

During the past few years, a growing number of groups have recognized the utility of microfluidic devices for environmental analysis. Microfluidic devices offer a number of advantages and in many respects are ideally suited to environmental analyses. Challenges faced...

Single-cell assay on microfluidic devices.

The Analyst

Huang Q, Mao S, Khan M, Lin JM.
PMID: 30177979
Analyst. 2019 Jan 28;144(3):808-823. doi: 10.1039/c8an01079j.

Advances in microfluidic techniques have prompted researchers to study the inherent heterogeneity of single cells in cell populations. This would be helpful in the identification of major diseases and the design of personalized medicine. Different microfluidic approaches provide a...

Capacitive coupling synchronizes autonomous microfluidic oscillators.

Electrophoresis

Lesher-Pérez SC, Zhang C, Takayama S.
PMID: 29383730
Electrophoresis. 2018 Apr;39(8):1096-1103. doi: 10.1002/elps.201700398. Epub 2018 Feb 23.

Even identically designed autonomous microfluidic oscillators have device-to-device oscillation variability that arises due to inconsistencies in fabrication, materials, and operation conditions. This work demonstrates, experimentally and theoretically, that with appropriate capacitive coupling these microfluidic oscillators can be synchronized. The...

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing.

Journal of visualized experiments : JoVE

Demaree B, Weisgerber D, Lan F, Abate AR.
PMID: 29889211
J Vis Exp. 2018 May 23;(135). doi: 10.3791/57598.

Sequencing technologies have undergone a paradigm shift from bulk to single-cell resolution in response to an evolving understanding of the role of cellular heterogeneity in biological systems. However, single-cell sequencing of large populations has been hampered by limitations in...

Microfluidic synthesis of nanomaterials.

Small (Weinheim an der Bergstrasse, Germany)

Song Y, Hormes J, Kumar CS.
PMID: 18535993
Small. 2008 Jun;4(6):698-711. doi: 10.1002/smll.200701029.

An overview of the current information and analyses on the microfluidic synthesis of different types of nanomaterial, including metallic and silica nanoparticles and quantum dots, is presented. Control of particle size, size distribution, and crystal structure of nanomaterials are...

Soft lithography: masters on demand.

Lab on a chip

Abdelgawad M, Watson MW, Young EW, Mudrik JM, Ungrin MD, Wheeler AR.
PMID: 18651082
Lab Chip. 2008 Aug;8(8):1379-85. doi: 10.1039/b804050h. Epub 2008 Jun 24.

We report an ultra-rapid prototyping technique for forming microchannel networks for lab-on-a-chip applications, called masters on-demand. Channels are produced by replica molding on masters formed by laser printing on flexible copper printed circuit board (PCB) substrates. Masters of various...

Showing 1 to 12 of 83 entries