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Showing 1 to 12 of 12 entries
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Fighting fire with fire: rewiring tumor cells for oncolytic virotherapy.

Future oncology (London, England)

Mahoney DJ, Stojdl DF.
PMID: 22409457
Future Oncol. 2012 Mar;8(3):219-21. doi: 10.2217/fon.12.2.

No abstract available.

Achieving systemic delivery of oncolytic viruses.

Expert opinion on drug delivery

Hill C, Carlisle R.
PMID: 31144549
Expert Opin Drug Deliv. 2019 Jun;16(6):607-620. doi: 10.1080/17425247.2019.1617269. Epub 2019 May 30.

AREAS COVERED: This review catalogs the techniques used to enhance OV delivery. Firstly, insights from clinical trials of OV provide evidence of the need for enhanced delivery strategies. Secondly, the techniques applied to overcome the challenges highlighted by clinical...

Redemption for the field of oncolytic virotherapy.

Molecular therapy : the journal of the American Society of Gene Therapy

Kirn DH.
PMID: 21455205
Mol Ther. 2011 Apr;19(4):627-8. doi: 10.1038/mt.2011.45.

No abstract available.

Recent advances in the development of oncolytic viruses as cancer therapeutics. Foreword.

Cytokine & growth factor reviews

Bell J, Kirn D.
PMID: 20444639
Cytokine Growth Factor Rev. 2010 Apr-Jun;21(2):83-4. doi: 10.1016/j.cytogfr.2010.04.004. Epub 2010 May 04.

No abstract available.

The emerging role of oncolytic virus therapy against cancer.

Chinese clinical oncology

Russell L, Peng KW.
PMID: 29764161
Chin Clin Oncol. 2018 Apr;7(2):16. doi: 10.21037/cco.2018.04.04.

This review discusses current clinical advancements in oncolytic viral therapy, with a focus on the viral platforms approved for clinical use and highlights the benefits each platform provides. Three oncolytic viruses (OVs), an echovirus, an adenovirus, and a herpes...

Reovirus: viral therapy for cancer 'as nature intended'.

Clinical oncology (Royal College of Radiologists (Great Britain))

Comins C, Heinemann L, Harrington K, Melcher A, De Bono J, Pandha H.
PMID: 18583112
Clin Oncol (R Coll Radiol). 2008 Sep;20(7):548-54. doi: 10.1016/j.clon.2008.04.018. Epub 2008 Jun 25.

Oncolytic viruses are tumour selective and able to lyse cancer cells after infection. Reovirus is an example of a wild-type oncolytic virus and is currently being investigated as a potential novel therapy for cancer. This overview gives a brief...

Navigating the clinical development landscape for oncolytic viruses and other cancer therapeutics: no shortcuts on the road to approval.

Cytokine & growth factor reviews

Breitbach CJ, Reid T, Burke J, Bell JC, Kirn DH.
PMID: 20472490
Cytokine Growth Factor Rev. 2010 Apr-Jun;21(2):85-9. doi: 10.1016/j.cytogfr.2010.02.001. Epub 2010 May 15.

Chemotherapy remains a common mode of anticancer treatment even though in most cancer indications the therapeutic approach is not effective and ultimately associated with the onset of chemoresistance. A better understanding of genetic differences in tumors ushered in the...

Personalized virotherapy in cancer.

Aging

Cafferata EG, Podhajcer OL.
PMID: 26022702
Aging (Albany NY). 2015 May;7(5):288-9. doi: 10.18632/aging.100750.

No abstract available.

Oncolytic viruses from the perspective of the immune system.

Future microbiology

Alemany R, Cascallo M.
PMID: 19492964
Future Microbiol. 2009 Jun;4(5):527-36. doi: 10.2217/fmb.09.28.

Cancer treatment with oncolytic viruses is at a crucial intersection from where two very different routes can be taken. The key role of the immune system needs to be addressed proactively to succeed. An immunocentric point of view posits...

Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Cancer gene therapy

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.
PMID: 30177818
Cancer Gene Ther. 2019 Mar;26(3):59-73. doi: 10.1038/s41417-018-0042-1. Epub 2018 Sep 04.

The 11th International Oncolytic Virus Conference (IOVC) was held from April 9-12, 2018 in Oxford, UK. This is part of the high-profile academic-led series of meetings that was started back in 2002 by Steve Russell and John Bell, with...

Harnessing the Power of Onco-Immunotherapy with Checkpoint Inhibitors.

Viruses

Rajani KR, Vile RG.
PMID: 26580645
Viruses. 2015 Nov 13;7(11):5889-901. doi: 10.3390/v7112914.

Oncolytic viruses represent a diverse class of replication competent viruses that curtail tumor growth. These viruses, through their natural ability or through genetic modifications, can selectively replicate within tumor cells and induce cell death while leaving normal cells intact....

Current strategies of virotherapy in clinical trials for cancer treatment.

Journal of medical virology

Lin W, Zhao Y, Zhong L.
PMID: 33738818
J Med Virol. 2021 Aug;93(8):4668-4692. doi: 10.1002/jmv.26947. Epub 2021 Apr 23.

As a novel immune-active agent for cancer treatment, viruses haveĀ the ability of infecting and replicating in tumor cells. The safety and efficacy of viruses hasĀ been tested and confirmed in preclinical and clinical trials. In the last decade,...

Showing 1 to 12 of 12 entries