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Showing 1 to 4 of 4 entries
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Immune Conversion of Tumor Microenvironment by Oncolytic Viruses: The Protoparvovirus H-1PV Case Study.

Frontiers in immunology

Marchini A, Daeffler L, Pozdeev VI, Angelova A, Rommelaere J.
PMID: 31440242
Front Immunol. 2019 Aug 07;10:1848. doi: 10.3389/fimmu.2019.01848. eCollection 2019.

Cancer cells utilize multiple mechanisms to evade and suppress anticancer immune responses creating a "cold" immunosuppressive tumor microenvironment. Oncolytic virotherapy is emerging as a promising approach to revert tumor immunosuppression and enhance the efficacy of other forms of immunotherapy....

Oncolytic viruses from the perspective of the immune system.

Future microbiology

Alemany R, Cascallo M.
PMID: 19492964
Future Microbiol. 2009 Jun;4(5):527-36. doi: 10.2217/fmb.09.28.

Cancer treatment with oncolytic viruses is at a crucial intersection from where two very different routes can be taken. The key role of the immune system needs to be addressed proactively to succeed. An immunocentric point of view posits...

Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Cancer gene therapy

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.
PMID: 30177818
Cancer Gene Ther. 2019 Mar;26(3):59-73. doi: 10.1038/s41417-018-0042-1. Epub 2018 Sep 04.

The 11th International Oncolytic Virus Conference (IOVC) was held from April 9-12, 2018 in Oxford, UK. This is part of the high-profile academic-led series of meetings that was started back in 2002 by Steve Russell and John Bell, with...

Making Oncolytic Virotherapy a Clinical Reality: The European Contribution.

Human gene therapy

Duffy MR, Fisher KD, Seymour LW.
PMID: 28793793
Hum Gene Ther. 2017 Nov;28(11):1033-1046. doi: 10.1089/hum.2017.112. Epub 2017 Aug 01.

Oncolytic viruses (OVs) are quickly moving toward the forefront of modern medicines. The reward for the decades of research invested into developing viral platforms that selectively replicate in and lyse tumor cells while sparking anticancer adaptive immunity is presenting...

Showing 1 to 4 of 4 entries