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Semi-synthetic approaches to novel penicillins.

Trends in biochemical sciences

Nayler JH.
PMID: 1891804
Trends Biochem Sci. 1991 Jun;16(6):234-7. doi: 10.1016/0968-0004(91)90092-a.

The first part of this account of the discovery of penicillin, published in last month's issue of TIBS, concluded with the detection of 6-beta-amino-penicillanic acid (6-APA), the nucleus of the penicillin structure. The exploitation of 6-APA led to the...

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