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Showing 1 to 12 of 286 entries
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Preparing pathology for precision medicine: challenges and opportunities.

Virchows Archiv : an international journal of pathology

Kaul KL.
PMID: 28512674
Virchows Arch. 2017 Aug;471(2):141-146. doi: 10.1007/s00428-017-2141-z. Epub 2017 May 16.

No abstract available.

Future of the Prevention and Treatment of Coronary Artery Disease.

Circulation journal : official journal of the Japanese Circulation Society

Steg PG, Ducrocq G.
PMID: 27063295
Circ J. 2016 Apr 25;80(5):1067-72. doi: 10.1253/circj.CJ-16-0266. Epub 2016 Apr 08.

With ongoing progress in the prevention and treatment of coronary artery disease (CAD), a continued decrease in prevalence and lethality is expected in high-income countries. Prevention will include lipid-lowering, antithrombotic and anti-inflammatory therapies. With respect to the former, potent,...

Therapeutic inertia or individualization? Delay in clinical management of type 2 diabetes mellitus.

Current medical research and opinion

Tanaka N, Kurose T, Seino Y.
PMID: 27181181
Curr Med Res Opin. 2016 Sep;32(9):1477-8. doi: 10.1080/03007995.2016.1190701. Epub 2016 Jun 13.

No abstract available.

Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities.

Genome medicine

Beckmann JS, Lew D.
PMID: 27993174
Genome Med. 2016 Dec 19;8(1):134. doi: 10.1186/s13073-016-0388-7.

This era of groundbreaking scientific developments in high-resolution, high-throughput technologies is allowing the cost-effective collection and analysis of huge, disparate datasets on individual health. Proper data mining and translation of the vast datasets into clinically actionable knowledge will require...

Integrative omics for health and disease.

Nature reviews. Genetics

Karczewski KJ, Snyder MP.
PMID: 29479082
Nat Rev Genet. 2018 May;19(5):299-310. doi: 10.1038/nrg.2018.4. Epub 2018 Feb 26.

Advances in omics technologies - such as genomics, transcriptomics, proteomics and metabolomics - have begun to enable personalized medicine at an extraordinarily detailed molecular level. Individually, these technologies have contributed medical advances that have begun to enter clinical practice....

Chronic disease prevention in primary care: how and when will genomics impact?.

The British journal of general practice : the journal of the Royal College of General Practitioners

Walter FM, Emery J, Burton H.
PMID: 24982473
Br J Gen Pract. 2014 Jul;64(624):331-2. doi: 10.3399/bjgp14X680401.

No abstract available.

[What of "personalized medicine" is really the name?].

Revue medicale suisse

Nau JY.
PMID: 26638521
Rev Med Suisse. 2015 Oct 07;11(489):1868-9.

No abstract available.

[The healthy man: a social animal].

Revue medicale suisse

Kiefer B.
PMID: 24834656
Rev Med Suisse. 2014 Apr 16;10(426):896.

No abstract available.

[Pathology in the era of personlized medicine].

Zhonghua bing li xue za zhi = Chinese journal of pathology

Liu TH.
PMID: 18844027
Zhonghua Bing Li Xue Za Zhi. 2008 Apr;37(4):217-8.

No abstract available.

Whether it is personalized, precision, or mechanistic medicine--- the clinical laboratory has a role.

Clinical biochemistry

Kavsak PA.
PMID: 22424084
Clin Biochem. 2012 Apr;45(6):384. doi: 10.1016/j.clinbiochem.2012.03.002.

No abstract available.

Current priorities for public health practice in addressing the role of human genomics in improving population health.

American journal of preventive medicine

Khoury MJ, Bowen MS, Burke W, Coates RJ, Dowling NF, Evans JP, Reyes M, St Pierre J.
PMID: 21406285
Am J Prev Med. 2011 Apr;40(4):486-93. doi: 10.1016/j.amepre.2010.12.009.

In spite of accelerating human genome discoveries in a wide variety of diseases of public health significance, the promise of personalized health care and disease prevention based on genomics has lagged behind. In a time of limited resources, public...

New technologies personalize diagnostics and therapeutics.

Current atherosclerosis reports

Rosenson RS.
PMID: 20425257
Curr Atheroscler Rep. 2010 May;12(3):184-6. doi: 10.1007/s11883-010-0103-x.

Atherosclerotic cardiovascular disease remains the leading cause of morbidity and mortality in industrialized societies [10]. Efforts to reduce cardiovascular events in "high-risk" individuals or recurrent events in patients with established atherosclerotic cardiovascular disease emphasize broad-based implementation of guideline-directed therapeutic...

Showing 1 to 12 of 286 entries