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Showing 1 to 12 of 41 entries
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Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing.

Cancer biology & therapy

Ikeda S, Elkin SK, Tomson BN, Carter JL, Kurzrock R.
PMID: 30339521
Cancer Biol Ther. 2019;20(2):219-226. doi: 10.1080/15384047.2018.1523849. Epub 2018 Oct 19.

Despite being one of the most common cancers, treatment options for prostate cancer are limited. Novel approaches for advanced disease are needed. We evaluated the relative rate of use of clinical-grade next generation sequencing (NGS) in prostate cancer, as...

Re: Delila Gasi Tandefelt, Joost L. Boormans, Hetty A. van der Korput, Guido W. Jenster, Jan Trapman. A 36-gene signature predicts clinical progression in a subgroup of ERG-positive prostate cancers. Eur Urol 2013;64:941-50.

European urology

Sampson N, Berger P, Klocker H.
PMID: 24565966
Eur Urol. 2014 Jun;65(6):e102-3. doi: 10.1016/j.eururo.2014.01.038. Epub 2014 Feb 10.

No abstract available.

Intraductal carcinoma of the prostate: the whole story.

Pathology

Zhou M.
PMID: 24018805
Pathology. 2013 Oct;45(6):533-9. doi: 10.1097/PAT.0b013e3283653322.

Intraductal carcinoma of the prostate (IDC-P) is characterised by proliferation of malignant secretory cells that markedly expand prostatic ducts and acini. Its morphological features and diagnostic criteria have been refined in recent studies. Its molecular characteristics have also been...

MicroRNA detection in prostate tumors by quantitative real-time PCR (qPCR).

Journal of visualized experiments : JoVE

Gordanpour A, Nam RK, Sugar L, Bacopulos S, Seth A.
PMID: 22643910
J Vis Exp. 2012 May 16;(63):e3874. doi: 10.3791/3874.

MicroRNAs (miRNAs) are single-stranded, 18-24 nucleotide long, non-coding RNA molecules. They are involved in virtually every cellular process including development, apoptosis, and cell cycle regulation. MiRNAs are estimated to regulate the expression of 30% to 90% of human genes...

Recurrent gene fusions in prostate cancer.

Nature reviews. Cancer

Kumar-Sinha C, Tomlins SA, Chinnaiyan AM.
PMID: 18563191
Nat Rev Cancer. 2008 Jul;8(7):497-511. doi: 10.1038/nrc2402. Epub 2008 Jun 19.

The discovery of recurrent gene fusions in a majority of prostate cancers has important clinical and biological implications in the study of common epithelial tumours. Gene fusion and chromosomal rearrangements were previously thought to be primarily the oncogenic mechanism...

'Working toward understanding oligo and polymetastatic prostate cancer'.

Current opinion in urology

Chapin BF, Bellmunt J.
PMID: 28922341
Curr Opin Urol. 2017 Nov;27(6):532. doi: 10.1097/MOU.0000000000000451.

No abstract available.

Genetic predisposition to prostate cancer: Update and future perspectives.

Urologic oncology

Demichelis F, Stanford JL.
PMID: 24996773
Urol Oncol. 2015 Feb;33(2):75-84. doi: 10.1016/j.urolonc.2014.04.021. Epub 2014 Jul 02.

OBJECTIVE: Prostate cancer is the second most frequent cancer in men worldwide and kills over 250,000 men worldwide every year. Prostate cancer is a heterogeneous disease at the clinical and the molecular level. The Scandinavian Twin Registry Study demonstrated...

Identifying an ERG-positive subclass with clinical progression using expression profiling.

European urology

Sboner A, Rubin MA.
PMID: 23557717
Eur Urol. 2013 Dec;64(6):951-2. doi: 10.1016/j.eururo.2013.03.036. Epub 2013 Mar 26.

No abstract available.

Clinical uncertainty of prostate cancer genetic risk panels.

Science translational medicine

Pomerantz M, Freedman ML.
PMID: 23616119
Sci Transl Med. 2013 Apr 24;5(182):182ed6. doi: 10.1126/scitranslmed.3004696.

No abstract available.

Genetically proxied morning chronotype was associated with a reduced risk of prostate cancer.

Sleep

Sun X, Ye D, Jiang M, Qian Y, Mao Y.
PMID: 33878190
Sleep. 2021 Oct 11;44(10). doi: 10.1093/sleep/zsab104.

STUDY OBJECTIVES: Observational epidemiological studies have suggested that chronotype may play a role in the pathogenesis and progression of prostate cancer. However, whether there is a causal association remains unknown. The aim of the present study was to examine...

[Bioinformatics-based identification of the key genes associated with prostate cancer].

Zhonghua nan ke xue = National journal of andrology

Zhao HB, Xu GB, Yang WQ, Li XZ, Chen SX, Gan Y, Su ZM, Sheng M, Zeng YR.
PMID: 34914287
Zhonghua Nan Ke Xue. 2021 Jun;27(6):489-498.

OBJECTIVE: To identify the key genes associated with the pathogenesis of PCa using the bioinformatics approach for a deeper insight into the molecular mechanisms underlying the development and progression of PCa.METHODS: The microarray datasets GSE70770, GSE32571 and GSE46602 were...

What is the significance of race to prostate carcinoma?.

Cancer

Bostwick DG.
PMID: 10463964
Cancer. 1999 Sep 01;86(5):735-7. doi: 10.1002/(sici)1097-0142(19990901)86:5<735::aid-cncr1>3.0.co;2-r.

No abstract available.

Showing 1 to 12 of 41 entries