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Showing 1 to 5 of 5 entries
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Generation of functional cardiac microtissues in a beating heart-on-a-chip.

Methods in cell biology

Ugolini GS, Visone R, Cruz-Moreira D, Mainardi A, Rasponi M.
PMID: 30037467
Methods Cell Biol. 2018;146:69-84. doi: 10.1016/bs.mcb.2018.05.005. Epub 2018 Jul 09.

With the increasing attention on cardiovascular disorders and the current inability of pre-clinical models to accurately predict human physiology, the need for advanced and reliable heart in vitro models is paramount. Microfabrication technologies provide potential solutions in the organs-on-chip...

Stem cells: to be born great, achieve greatness, or have greatness thrust upon them?.

Integrative biology : quantitative biosciences from nano to macro

Tran R, Hoesli CA, Moraes C.
PMID: 27367801
Integr Biol (Camb). 2016 Jul 11;8(7):737-40. doi: 10.1039/c6ib90021f.

Induced pluripotent stem cells (iPSCs) have opened new doors in providing an ethical, patient-specific cell source towards tissue engineering. Developing these therapies involves the production of reprogrammed iPSCs, expanding them while maintaining pluripotency, then differentiating them into functional tissues....

Hydrodynamics of the Bio-Gripper: A Fluid-Driven "Claw Machine" for Soft Microtissue Translocation.

SLAS technology

Cui FR, Ip BC, Morgan JR, Tripathi A.
PMID: 29932848
SLAS Technol. 2018 Dec;23(6):540-549. doi: 10.1177/2472630318775079. Epub 2018 Jun 22.

Technological advances in solid organ tissue engineering that rely on the assembly of small tissue-building parts require a novel transport method suited for soft, deformable, living objects of submillimeter- to centimeter-length scale. We describe a technology that utilizes membrane...

Mini-review: advances in 3D bioprinting of vascularized constructs.

Biology direct

Bova L, Billi F, Cimetta E.
PMID: 33138851
Biol Direct. 2020 Nov 02;15(1):22. doi: 10.1186/s13062-020-00273-4.

3D in vitro constructs have gained more and more relevance in tissue engineering and in cancer-modeling. In recent years, with the development of thicker and more physiologically relevant tissue patches, the integration of a vascular network has become pivotal,...

Bio-Pick, Place, and Perfuse: A New Instrument for Three-Dimensional Tissue Engineering.

Tissue engineering. Part C, Methods

Blakely AM, Manning KL, Tripathi A, Morgan JR.
PMID: 25530515
Tissue Eng Part C Methods. 2015 Jul;21(7):737-46. doi: 10.1089/ten.TEC.2014.0439. Epub 2015 Feb 09.

A grand challenge of tissue engineering is the fabrication of large constructs with a high density of living cells. By adapting the principles of pick-and-place machines used in the high-speed assembly of electronics, we have developed an innovative instrument,...

Showing 1 to 5 of 5 entries