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Showing 1 to 9 of 9 entries
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MicroRNAs and triple negative breast cancer.

International journal of molecular sciences

D'Ippolito E, Iorio MV.
PMID: 24284394
Int J Mol Sci. 2013 Nov 11;14(11):22202-20. doi: 10.3390/ijms141122202.

Triple Negative Breast Cancer (TNBC) is a very aggressive tumor subtype, which still lacks specific markers for an effective targeted therapy. Despite the common feature of negativity for the three most relevant receptors (ER, PgR and HER2), TNBC is...

Optimal co-clinical radiomics: Sensitivity of radiomic features to tumour volume, image noise and resolution in co-clinical T1-weighted and T2-weighted magnetic resonance imaging.

EBioMedicine

Roy S, Whitehead TD, Quirk JD, Salter A, Ademuyiwa FO, Li S, An H, Shoghi KI.
PMID: 32891051
EBioMedicine. 2020 Sep;59:102963. doi: 10.1016/j.ebiom.2020.102963. Epub 2020 Sep 02.

BACKGROUND: Radiomics analyses has been proposed to interrogate the biology of tumour as well as to predict/assess response to therapy in vivo. The objective of this work was to assess the sensitivity of radiomics features to noise, resolution, and...

Basal-like and triple-negative breast cancers: searching for positives among many negatives.

Surgical oncology clinics of North America

Alluri P, Newman LA.
PMID: 24882351
Surg Oncol Clin N Am. 2014 Jul;23(3):567-77. doi: 10.1016/j.soc.2014.03.003.

Triple-negative breast cancers (TNBC) are defined by their failure to express the estrogen receptor, progesterone receptor, and HER2/neu protein markers. This basic feature is clinically relevant because it indicates that these cancers cannot be managed with endocrine or anti-HER2...

Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype?.

Oncotarget

Le Du F, Eckhardt BL, Lim B, Litton JK, Moulder S, Meric-Bernstam F, Gonzalez-Angulo AM, Ueno NT.
PMID: 25973541
Oncotarget. 2015 May 30;6(15):12890-908. doi: 10.18632/oncotarget.3849.

Significant research has been conducted to better understand the extensive, heterogeneous molecular features of triple-negative breast cancer (TNBC). We reviewed published TNBC molecular classifications to identify major groupings that have potential for clinical trial development. With the ultimate aim...

Dr Sandi Dunn illuminates emerging key treatment approaches and companion diagnostics for triple negative breast cancer.

Expert opinion on investigational drugs

Dunn S.
PMID: 33070643
Expert Opin Investig Drugs. 2020 Dec;29(12):1309-1312. doi: 10.1080/13543784.2020.1839847. Epub 2020 Oct 31.

No abstract available.

Subtyping of triple-negative breast cancer.

Clinical advances in hematology & oncology : H&O

Mayer IA.
PMID: 24896546
Clin Adv Hematol Oncol. 2013 Nov;11(11):731-2.

No abstract available.

Metastatic triple negative breast cancer: Optimizing treatment options, new and emerging targeted therapies.

Asia-Pacific journal of clinical oncology

Khosravi-Shahi P, Cabezón-Gutiérrez L, Custodio-Cabello S.
PMID: 28815913
Asia Pac J Clin Oncol. 2018 Feb;14(1):32-39. doi: 10.1111/ajco.12748. Epub 2017 Aug 16.

Triple negative breast cancer (TNBC) is a heterogeneous disease, not only on the molecular level, but also on the pathologic and clinical levels. It also has a distinct epidemiology. TNBCs are frequently of high histologic grade, typically more aggressive...

Ensemble outlier detection and gene selection in triple-negative breast cancer data.

BMC bioinformatics

Lopes MB, Veríssimo A, Carrasquinha E, Casimiro S, Beerenwinkel N, Vinga S.
PMID: 29728051
BMC Bioinformatics. 2018 May 04;19(1):168. doi: 10.1186/s12859-018-2149-7.

BACKGROUND: Learning accurate models from 'omics data is bringing many challenges due to their inherent high-dimensionality, e.g. the number of gene expression variables, and comparatively lower sample sizes, which leads to ill-posed inverse problems. Furthermore, the presence of outliers,...

MicroRNA-based potential diagnostic, prognostic and therapeutic applications in triple-negative breast cancer.

Artificial cells, nanomedicine, and biotechnology

Tang Q, Ouyang H, He D, Yu C, Tang G.
PMID: 31284781
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2800-2809. doi: 10.1080/21691401.2019.1638791.

Triple-negative breast cancer (TNBC) is a distinct subtype of breast cancer characterized by high recurrence rates and poor prognosis compared to other breast cancers. MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of various post-transcriptional gene and...

Showing 1 to 9 of 9 entries