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Ciminiello P, Dell'Aversano C, Fattorusso E, et al. Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis . J Nat Prod. 1999;62(4):590-3doi: 10.1021/np9805138.
Ciminiello, P., Dell'Aversano, C., Fattorusso, E., Magno, S., & Pansini, M. (1999). Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis . Journal of natural products, 62(4), 590-3. https://doi.org/10.1021/np9805138
Ciminiello, et al. "Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis ." Journal of natural products vol. 62,4 (1999): 590-3. doi: https://doi.org/10.1021/np9805138
Ciminiello P, Dell'Aversano C, Fattorusso E, Magno S, Pansini M. Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis . J Nat Prod. 1999 Apr;62(4):590-3. doi: 10.1021/np9805138. PMID: 10217716.
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American Chemical Society

J Nat Prod. 1999 Apr;62(4):590-3. doi: 10.1021/np9805138.

Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis .

Journal of natural products

Ciminiello, Dell'Aversano, Fattorusso, Magno, Pansini

Affiliations

  1. Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli "Federico II", Via D. Montesano 49, 80131 Napoli, Italy, and Istituto di Zoologia, Via Balbi 5, 16126 Genova, Italy.

PMID: 10217716 DOI: 10.1021/np9805138

Abstract

A detailed analysis of the secondary metabolites of the sponge Aplysina cauliformis has been performed. Eight compounds were identified, two of which (13 and 14) are new bromotyrosine derivatives whose structures were determinated from spectroscopic evidence, including 2D NMR. The new compounds were analyzed for cytotoxic activity, and compound 14 was shown to inhibit mammalian protein synthesis and cell proliferation.

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