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Kubanek J, Andersen RJ. Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis . J Nat Prod. 1999;62(5):777-9doi: 10.1021/np9804839.
Kubanek, J., & Andersen, R. J. (1999). Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis . Journal of natural products, 62(5), 777-9. https://doi.org/10.1021/np9804839
Kubanek, and Andersen. "Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis ." Journal of natural products vol. 62,5 (1999): 777-9. doi: https://doi.org/10.1021/np9804839
Kubanek J, Andersen RJ. Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis . J Nat Prod. 1999 May;62(5):777-9. doi: 10.1021/np9804839. PMID: 10346969.
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J Nat Prod. 1999 May;62(5):777-9. doi: 10.1021/np9804839.

Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis .

Journal of natural products

Kubanek, Andersen

Affiliations

  1. Departments of Chemistry and Oceanography-Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.

PMID: 10346969 DOI: 10.1021/np9804839

Abstract

Stable isotope incorporation experiments using sodium [1, 2-13C2]acetate have demonstrated that the 3-hydroxybutyrate substituent of diaulusterol A (1) is biosynthesized de novo by the dorid nudibranch Diaulula sandiegensis. There was no evidence for acetate incorporation into the steroid portion of 1, nor were radiolabeled mevalonate or cholesterol incorporated.

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