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Rapid Commun Mass Spectrom. 1999 Jun;13(12):1165-1168. doi: 10.1002/(SICI)1097-0231(19990630)13:12<1165::AID-RCM638>3.0.CO;2-4.

High throughput liquid chromatography/mass spectrometric analyses using a novel multiplexed electrospray interface.

Rapid communications in mass spectrometry : RCM

de Biasi V, Haskins, Organ, Bateman, Giles, Jarvis

Affiliations

  1. SmithKline Beecham Pharmaceuticals, Harlow, Essex CM19 5AD, UK.

PMID: 10407292 DOI: 10.1002/(SICI)1097-0231(19990630)13:12<1165::AID-RCM638>3.0.CO;2-4

Abstract

A novel four- channel multiplexed electrospray liquid chromatography interface is described. This device has been used to analyse both single components and mixtures by liquid chromatography/mass spectrometry (LC/MS) as well as synthetic samples prepared by automated procedures. These data provided unambiguous molecular weight assignments to both major components and synthetic by-products in these samples. In this work particular attention has also been paid to the elimination of interchannel crosstalk. Copyright 1999 John Wiley & Sons, Ltd.

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