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Schluesener H. Tyrosyl-tRNA Synthetase: A Housekeeping Protein and an Attractive Harbinger of Cellular Death. Angew Chem Int Ed Engl. 1999;38(24):3635-3637
Schluesener, H. (1999). Tyrosyl-tRNA Synthetase: A Housekeeping Protein and an Attractive Harbinger of Cellular Death. Angewandte Chemie (International ed. in English), 38(24), 3635-3637.
Schluesener. "Tyrosyl-tRNA Synthetase: A Housekeeping Protein and an Attractive Harbinger of Cellular Death." Angewandte Chemie (International ed. in English) vol. 38,24 (1999): 3635-3637.
Schluesener H. Tyrosyl-tRNA Synthetase: A Housekeeping Protein and an Attractive Harbinger of Cellular Death. Angew Chem Int Ed Engl. 1999 Dec 16;38(24):3635-3637. PMID: 10649308.
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Angew Chem Int Ed Engl. 1999 Dec 16;38(24):3635-3637.

Tyrosyl-tRNA Synthetase: A Housekeeping Protein and an Attractive Harbinger of Cellular Death.

Angewandte Chemie (International ed. in English)

Schluesener

Affiliations

  1. Institut für Hirnforschung der Universität, Calwer Strasse 3, D-72076 Tübingen (Germany).

PMID: 10649308

Abstract

Cytokine-type activities are observed for the human tyrosyl-tRNA synthetase, largely considered as an essential enzyme for protein synthesis, only after cleavage into two fragments. These peptide fragments are novel elements in the orchestration of the tissue response to a cellular suicide program and should be viewed as highly differentiated adaptions of peptide modules with biological activity in more than one kind of environment.

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