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Adv Drug Deliv Rev. 1998 May 04;31(3):223-246. doi: 10.1016/s0169-409x(97)00120-8.

Inclusion and release of proteins from polysaccharide-based polyion complexes.

Advanced drug delivery reviews

Chornet, Dumitriu

Affiliations

  1. University of Sherbrooke, Departement of Chemical Engineering, Sherbrooke, PQ, J1K 2R1, Canada

PMID: 10837627 DOI: 10.1016/s0169-409x(97)00120-8

Abstract

The notion of a polyelectrolyte complex is well established for the complexation of two polymers one anionic, the other cationic. Electronic microscopy studies have shown the formation of a fibrilar structure. A method for the preparation of polyionic hydrogels from the complexation of chitosan and xanthan is reported. Electronic microscopy studies have shown the formation of a fibrilar structure. Stable hydrogels have been used to immobilize xylanase, lipase and protease. The immobilized xylanase and lipase activity was significantly higher than that of the free enzyme.

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