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Simoni D, Rossi M, Rondanin R, et al. Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions. Org Lett. 2000;2(24):3765-8doi: 10.1021/ol0001665.
Simoni, D., Rossi, M., Rondanin, R., Mazzali, A., Baruchello, R., Malagutti, C., Roberti, M., & Invidiata, F. P. (2000). Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions. Organic letters, 2(24), 3765-8. https://doi.org/10.1021/ol0001665
Simoni, et al. "Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions." Organic letters vol. 2,24 (2000): 3765-8. doi: https://doi.org/10.1021/ol0001665
Simoni D, Rossi M, Rondanin R, Mazzali A, Baruchello R, Malagutti C, Roberti M, Invidiata FP. Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions. Org Lett. 2000 Nov 30;2(24):3765-8. doi: 10.1021/ol0001665. PMID: 11101414.
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Org Lett. 2000 Nov 30;2(24):3765-8. doi: 10.1021/ol0001665.

Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions.

Organic letters

Simoni, Rossi, Rondanin, Mazzali, Baruchello, Malagutti, Roberti, Invidiata

Affiliations

  1. Dipartimento di Scienze Farmaceutiche, Universita di Ferrara, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy, Dipartimento di Scienze Farmaceutiche, Universita di Bologna, Via Belmeloro 6, 40126 Bologna, Italy, and Dipartimento Farmaco.

PMID: 11101414 DOI: 10.1021/ol0001665

Abstract

A convenient procedure to effect the Wittig and Horner-Wadsworth-Emmons reactions employs guanidine TBD and MTBD as base-promoters; mild reaction conditions, high efficiency, and facile isolation of the final products make the present methodology, at least in some cases, a practical alternative to known procedures.

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