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Cas Lek Cesk. 2000 Oct 25;139(21):647-51.

[Biochips].

Casopis lekaru ceskych

[Article in Czech]
G Rajská

Affiliations

  1. Krajská hygienická stanice Stredoceského kraje a Ustav experimentální medicíny AV CR, Praha.

PMID: 11192761

Abstract

A new revolution technology that may become promising for research, diagnostics and therapy enters into biology and medicine. The basic idea of the biochip technology is to convert the chemistry of life into a static form programmed to monitor genes, proteins and relations between them. Biochip programmed by known sequences of DNA/RNA or proteins can recognized the real genes, mutations, levels of expression,... Biochip technology is highly effective method that allows monitoring of thousands of genes/alleles at a time in computerized automatic operations with minimal volumes of necessary reagents. Biochips promise an important shift in molecular biology, DNA diagnostics, pharmacology, research in carcinogenesis and other diseases and also the possibility of a better understanding of the world of biology in its globality.

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