Display options
Cite
Aszalós A, Eckhardt S. Molecular Events as Targets of Anticancer Drug Therapy. Pathol Oncol Res. 1997;3(2):147-158doi: 10.1007/BF02907812.
Aszalós, A., & Eckhardt, S. (1997). Molecular Events as Targets of Anticancer Drug Therapy. Pathology oncology research : POR, 3(2), 147-158. https://doi.org/10.1007/BF02907812
Aszalós, Adorján, and Eckhardt, Sándor. "Molecular Events as Targets of Anticancer Drug Therapy." Pathology oncology research : POR vol. 3,2 (1997): 147-158. doi: https://doi.org/10.1007/BF02907812
Aszalós A, Eckhardt S. Molecular Events as Targets of Anticancer Drug Therapy. Pathol Oncol Res. 1997;3(2):147-158. doi: 10.1007/BF02907812. PMID: 11173644.
Copy Download .nbib Format: NLM
Share it on

Pathol Oncol Res. 1997;3(2):147-158. doi: 10.1007/BF02907812.

Molecular Events as Targets of Anticancer Drug Therapy.

Pathology oncology research : POR

Adorján Aszalós, Sándor Eckhardt

Affiliations

  1. Food and Drug Administration, Washington DC, USA.

PMID: 11173644 DOI: 10.1007/BF02907812

Abstract

The aim of this review is to introduce some molecular targets for cancer chemotherapy, with comments on their mode of action, preclinical and clinical results. The representatives of the following groups are covered: phosphorylation inhibitors, protein kinase modulators, receptor antagonists, immunomodulators, differentiating agents, multidrug resistance modulation, telomerase inhibitors, and bioreductive agents.

References

  1. Proc Natl Acad Sci U S A. 1987 Oct;84(20):7275-9 - PubMed
  2. Trends Biochem Sci. 1992 Oct;17(10):367-443 - PubMed
  3. Cancer Res. 1988 Dec 15;48(24 Pt 1):6977-85 - PubMed
  4. Cancer. 1993 Dec 15;72(12):3553-63 - PubMed
  5. Biochem Biophys Res Commun. 1995 Sep 25;214(3):1197-203 - PubMed
  6. Cancer Res. 1996 Apr 1;56(7):1621-8 - PubMed
  7. Eur J Cancer. 1996 Jun;32A(6):1070-81 - PubMed
  8. Cell Signal. 1995 Jul;7(5):431-43 - PubMed
  9. J Clin Endocrinol Metab. 1983 Apr;56(4):673-7 - PubMed
  10. Fortschr Chem Org Naturst. 1991;57:153-195 - PubMed
  11. Blood. 1990 Aug 15;76(4):716-20 - PubMed
  12. Int J Cancer. 1996 Jan 26;65(3):389-97 - PubMed
  13. J Natl Cancer Inst. 1993 Nov 17;85(22):1812-8 - PubMed
  14. Blood. 1992 Jan 15;79(2):299-303 - PubMed
  15. Nat Med. 1995 Mar;1(3):249-55 - PubMed
  16. Cancer Commun. 1990;2(9):297-303 - PubMed
  17. J Med Chem. 1996 Jan 5;39(1):224-36 - PubMed
  18. N Engl J Med. 1996 Jan 25;334(4):246-54 - PubMed
  19. Trends Biochem Sci. 1994 Nov;19(11):459-63 - PubMed
  20. J Invest Dermatol. 1990 Nov;95(5 Suppl):44S-46S - PubMed
  21. Eur J Gastroenterol Hepatol. 1995 Oct;7(10):971-4 - PubMed
  22. Methods Enzymol. 1990;190:217-25 - PubMed
  23. Eur J Cancer. 1991;27(10):1247-52 - PubMed
  24. Eur J Cancer. 1995 Jun;31A(6):969-73 - PubMed
  25. Br J Cancer. 1995 Apr;71(4):738-43 - PubMed
  26. Cancer Lett. 1995 Sep 4;96(1):81-5 - PubMed
  27. Anticancer Drugs. 1995 Jun;6(3):392-7 - PubMed
  28. Annu Rev Biochem. 1992;61:113-29 - PubMed
  29. Antiviral Res. 1992 Sep;19(3):233-45 - PubMed
  30. Cancer Chemother Pharmacol. 1995;36(1):7-12 - PubMed
  31. Cancer Treat Res. 1995;78:3-27 - PubMed
  32. Leuk Res. 1995 Oct;19(10):713-8 - PubMed
  33. Annu Rev Biochem. 1993;62:385-427 - PubMed
  34. Cancer Res. 1995 Oct 1;55(19):4214-9 - PubMed
  35. Blood. 1993 Jan 15;81(2):529-37 - PubMed
  36. J Immunol. 1988 Nov 15;141(10):3263-9 - PubMed
  37. Arterioscler Thromb Vasc Biol. 1995 Dec;15(12 ):2273-83 - PubMed
  38. Leuk Res. 1995 Oct;19(10):707-12 - PubMed
  39. J Urol. 1992 Jan;147(1):31-3 - PubMed
  40. Eur J Cancer. 1991;27(12 ):1639-42 - PubMed
  41. Biochem Pharmacol. 1993 Nov 17;46(10):1831-40 - PubMed
  42. Drug Intell Clin Pharm. 1988 Feb;22(2):134-6 - PubMed
  43. Pharmacol Ther. 1991;50(1):1-33 - PubMed
  44. J Biol Chem. 1993 Mar 15;268(8):5774-82 - PubMed
  45. J Clin Invest. 1995 Aug;96(2):1026-34 - PubMed
  46. Eur J Endocrinol. 1995 Dec;133(6):686-90 - PubMed
  47. J Cancer Res Clin Oncol. 1993;119(7):401-7 - PubMed
  48. J Immunol. 1983 Feb;130(2):965-9 - PubMed
  49. Ann Intern Med. 1986 Dec;105(6):856-61 - PubMed
  50. J Clin Endocrinol Metab. 1995 Dec;80(12):3395-402 - PubMed
  51. Surgery. 1989 Aug;106(2):416-22 - PubMed
  52. N Engl J Med. 1988 Jun 23;318(25):1633-7 - PubMed
  53. Br J Cancer. 1995 Nov;72 (5):1151-9 - PubMed
  54. Endocrinology. 1995 Jun;136(6):2513-20 - PubMed
  55. Pancreas. 1993 Jan;8(1):88-97 - PubMed
  56. Science. 1994 Dec 23;266(5193):2011-5 - PubMed
  57. Br J Cancer. 1996 Feb;73(4):433-8 - PubMed
  58. Eur J Cancer Clin Oncol. 1987 Sep;23(9):1283-7 - PubMed
  59. Eur J Cancer Prev. 1995 Dec;4(6):483-90 - PubMed
  60. FASEB J. 1991 Nov;5(14):2924-33 - PubMed
  61. Cancer Res. 1995 Sep 1;55(17):3716-20 - PubMed
  62. J Neurooncol. 1990 Feb;8(1):1-12 - PubMed
  63. Endocr Rev. 1991 Nov;12(4):450-82 - PubMed
  64. Pharmacol Ther. 1985;30(1):67-89 - PubMed
  65. J Pediatr Surg. 1995 Nov;30(11):1580-9 - PubMed
  66. Proc Natl Acad Sci U S A. 1989 Mar;86(6):2003-7 - PubMed
  67. Endocrinology. 1982 Oct;111(4):1394-6 - PubMed
  68. Nature. 1990 Jan 11;343(6254):177-80 - PubMed
  69. N Engl J Med. 1983 Dec 15;309(24):1495-501 - PubMed
  70. Cancer Treat Rev. 1989 Jun;16 Suppl A:115-21 - PubMed
  71. Cancer. 1983 Jan 1;51(1):9-14 - PubMed
  72. Cold Spring Harb Symp Quant Biol. 1994;59:307-15 - PubMed
  73. Cell. 1994 Apr 22;77(2):175-8 - PubMed
  74. Life Sci. 1980 Oct 13;27(15):1351-8 - PubMed
  75. Science. 1995 Sep 1;269(5228):1236-41 - PubMed
  76. J Cell Biochem Suppl. 1995;22:247-53 - PubMed
  77. Biochem Biophys Res Commun. 1996 Mar 27;220(3):795-801 - PubMed
  78. J Natl Cancer Inst. 1992 Nov 18;84(22):1736-40 - PubMed
  79. Cancer Treat Rep. 1984 Jan;68(1):199-205 - PubMed
  80. Eur J Clin Invest. 1987 Aug;17(4):281-7 - PubMed
  81. Cancer Res. 1995 Aug 1;55(15):3258-62 - PubMed
  82. Int J Cancer. 1993 May 28;54(3):456-61 - PubMed
  83. Pancreas. 1986;1(1):44-8 - PubMed
  84. Anticancer Res. 1989 Jul-Aug;9(4):889-91 - PubMed
  85. J Cell Physiol. 1996 Mar;166(3):631-6 - PubMed
  86. Science. 1992 Dec 4;258(5088):1650-4 - PubMed
  87. J Natl Cancer Inst. 1996 Jan 17;88(2):116-22 - PubMed
  88. Am J Surg. 1988 Jan;155(1):29-35 - PubMed
  89. J Natl Cancer Inst. 1992 Feb 19;84(4):235-41 - PubMed
  90. J Clin Endocrinol Metab. 1987 Oct;65(4):703-10 - PubMed
  91. Leuk Res. 1995 Sep;19(9):667-73 - PubMed
  92. Cancer Res. 1995 Oct 1;55(19):4243-7 - PubMed
  93. J Interferon Res. 1980 Fall;1(1):1-14 - PubMed
  94. Kaku Igaku. 1995 Nov;32(11):1269-80 - PubMed
  95. Hematol Oncol. 1990 Mar-Apr;8(2):81-9 - PubMed
  96. J Med Chem. 1992 Feb 21;35(4):687-94 - PubMed
  97. Blood. 1989 Oct;74(5):1747-57 - PubMed
  98. Proc Natl Acad Sci U S A. 1992 May 1;89(9):3942-6 - PubMed
  99. Int J Cancer. 1991 Aug 19;49(1):66-72 - PubMed
  100. Transplantation. 1991 Apr;51(4):847-50 - PubMed
  101. N Engl J Med. 1993 Jan 14;328(2):81-6 - PubMed
  102. Cancer Res. 1994 Aug 1;54(15):4123-8 - PubMed

Publication Types