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News Physiol Sci. 1999 Oct;14:201-206. doi: 10.1152/physiologyonline.1999.14.5.201.

Visceral Afferent Neurons: Role in Gastric Mucosal Protection.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Peter Holzer, Maria A. Pabst

Affiliations

  1. Department of Experimental and Clinical Pharmacology, University of Graz, Universitätsplatz 4, A-8010 Graz, Austria.

PMID: 11390851 DOI: 10.1152/physiologyonline.1999.14.5.201

Abstract

Gastric mucosal homeostasis requires rapid alarm of protective mechanisms in the face of pending injury. This article summarizes the evidence that spinal afferent neurons monitor insults to the gastric mucosa and activate local mechanisms of defense and repair through release of transmitter peptides from their endings in the stomach.

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