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News Physiol Sci. 2000 Feb;15:6-11. doi: 10.1152/physiologyonline.2000.15.1.6.

Bile Formation: a Concerted Action of Membrane Transporters in Hepatocytes and Cholangiocytes.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Akos Zsembery, Theresia Thalhammer, Jürg Graf

Affiliations

  1. Department of General and Experimental Pathology at the University Hospital Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.

PMID: 11390868 DOI: 10.1152/physiologyonline.2000.15.1.6

Abstract

A large number of membrane transport mechanisms in hepatocytes and cholangiocytes serves for the secretion of bile acids, various other organic anions, organic cations, lipids, and electrolytes. After their functional characterization, some of these mechanisms' individual transport molecules are now identified, allowing better understanding of inherited and acquired disorders of bile formation.

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