Display options
Cite
Melo LG, Pang SC, Ackermann U. Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure. News Physiol Sci. 2000;15:143-149doi: 10.1152/physiologyonline.2000.15.3.143.
Melo, L. G., Pang, S. C., & Ackermann, U. (2000). Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society, 15143-149. https://doi.org/10.1152/physiologyonline.2000.15.3.143
Melo, Luis Gabriel, et al. "Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure." News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society vol. 15 (2000): 143-149. doi: https://doi.org/10.1152/physiologyonline.2000.15.3.143
Melo LG, Pang SC, Ackermann U. Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure. News Physiol Sci. 2000 Jun;15:143-149. doi: 10.1152/physiologyonline.2000.15.3.143. PMID: 11390897.
Copy Download .nbib Format: NLM
Share it on

News Physiol Sci. 2000 Jun;15:143-149. doi: 10.1152/physiologyonline.2000.15.3.143.

Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Luis Gabriel Melo, Stephen C. Pang, Uwe Ackermann

Affiliations

  1. Department of Physiology of the University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

PMID: 11390897 DOI: 10.1152/physiologyonline.2000.15.3.143

Abstract

Recent findings in atrial natriuretic peptide (ANP) transgenic and gene knockout mouse models uncovered a tonic vasodilatory effect of this hormone that contributes to chronic blood pressure homeostasis. With elevated salt intake, ANP-mediated antagonism of the renin-angiotensin system is essential for blood pressure constancy, suggesting that a deficiency in ANP activity may underlie the etiology of sodium-retaining disorders.

Publication Types