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J Org Chem. 2001 Apr 20;66(8):2854-7. doi: 10.1021/jo001685o.

N-functionalized benzotriazole-1-carboximidoyl chlorides: synthetic equivalents for isocyanide dichlorides.

The Journal of organic chemistry

A R Katritzky, B Rogovoy, C Klein, H Insuasty, V Vvedensky, B Insuasty

Affiliations

  1. Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA. [email protected]

PMID: 11304212 DOI: 10.1021/jo001685o

Abstract

Readily prepared N-functionalized benzotriazole-1-carboximidoyl chlorides are proposed as stable and novel isocyanide dichloride synthetic equivalents. Subsequent condensations of these new intermediates afford polysubstituted guanidines, S-aryl isothioureas, and 2-aminoquinazolin-4-thiones.

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